Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | HPGD | P15428 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | FHIT | P49789 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9668675 | 0.88 | KDM4E (0.46) | KDM4EIDO1LMNAPKMALDH1A1 | |
| SCHEMBL10370830 | 0.87 | KDM4E (0.55) | KDM4EIDO1LMNAPKMALDH1A1 | |
| SCHEMBL10688342 | 0.86 | KDM4E (0.44) | KDM4EIDO1LMNAPKMALDH1A1 | |
| SCHEMBL10373253 | 0.84 | KDM4E (0.41) | KDM4EIDO1LMNAPKMALDH1A1 | |
| SCHEMBL10371885 | 0.84 | KDM4E (0.41) | KDM4EIDO1LMNAPKMALDH1A1 | |
| SCHEMBL9726388 | 0.84 | KDM4E (0.41) | KDM4EIDO1LMNAPKMALDH1A1 | |
| SCHEMBL9588985 | 0.84 | KDM4E (0.43) | KDM4EIDO1LMNAPKMALDH1A1 | |
| SCHEMBL9726332 | 0.83 | KDM4E (0.40) | KDM4EIDO1LMNAPKMALDH1A1 | |
| SCHEMBL9726407 | 0.82 | KDM4E (0.41) | KDM4EIDO1LMNAPKMALDH1A1 | |
| SCHEMBL9726286 | 0.82 | KDM4E (0.40) | KDM4EIDO1LMNAPKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0182769-B1 | 2,6-SUBSTITUTED PYRIDINE COMPOUNDS | Monsanto Company (US) | 1990-08-01 | — | — | EP | disclosed |
| US-4921530-A | Certain 3,5-pyridine dicarboxylates, their thio analogues having herbicidal activity | MONSANTO COMPANY (US) | 1990-05-01 | — | — | US | disclosed |
| US-4835279-A | 2,6-substituted pyridine compounds | MONSANTO COMPANY (US) | 1989-05-30 | — | — | US | disclosed |
| US-4797149-A | HERBICIDES | MONSANTO COMPANY (US) | 1989-01-10 | — | — | US | disclosed |
| US-4698093-A | POST, PRE EMERGENTS | MONSANTO COMPANY (US) | 1987-10-06 | — | — | US | disclosed |
| EP-0182769-A1 | 2,6-Substituted pyridine compounds | Monsanto Company (US) | 1986-05-28 | — | — | EP | disclosed |