Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11165560 | 0.72 | — | — | |
| SCHEMBL10581081 | 0.71 | — | — | |
| SCHEMBL8934634 | 0.68 | — | — | |
| SCHEMBL19472118 | 0.68 | NQO1 (0.33) | NQO1 | |
| SCHEMBL12336961 | 0.62 | — | — | |
| SCHEMBL19474632 | 0.61 | — | — | |
| SCHEMBL19474633 | 0.60 | — | — | |
| SCHEMBL7556255 | 0.60 | — | — | |
| SCHEMBL6357054 | 0.58 | — | — | |
| SCHEMBL4591293 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0129051-B1 | SUBSTITUTED INDOLES | CIBA-GEIGY AG (CH) | 1990-07-04 | — | — | EP | disclosed |
| EP-0093084-B1 | 1-CARBOXYALKANOYLINDOLINE-2-CARBOXYLIC-ACID ESTERS, THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR THERAPEUTIC USE | CIBA-GEIGY AG (CH) | 1986-03-12 | — | — | EP | disclosed |
| EP-0129051-A2 | Substituted indoles | CIBA-GEIGY AG (CH) | 1984-12-27 | — | — | EP | disclosed |
| EP-0126401-A1 | Indole compounds | CIBA-GEIGY AG (CH) | 1984-11-28 | — | — | EP | disclosed |
| EP-0093084-A1 | 1-Carboxyalkanoylindoline-2-carboxylic-acid esters, their preparation, pharmaceutical compositions containing them, and their therapeutic use | CIBA-GEIGY AG (CH) | 1983-11-02 | — | — | EP | disclosed |