SCHEMBL10374243

SCHEMBL10374243

N#CCN1C(=O)COc2cc(F)c(N3C(=O)C4=C(CCCC4)C3=O)cc21

nearest known ligand 0.80

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GRM7 Q14831 2/20 0.37
GRM4 Q14833 2/20 0.37
GRM1 Q13255 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Flumioxazin SCHEMBL39699 0.89 GRM1 (0.37) GRM7GRM4GRM1
Flumioxazin SCHEMBL29539500 0.89 GRM1 (0.37) GRM7GRM4GRM1
Flumioxazin SCHEMBL29088353 0.88 GRM1 (0.37) GRM7GRM4GRM1
Flumioxazin SCHEMBL19641848 0.85 GRM1 (0.39) GRM7GRM4GRM1
SCHEMBL10376307 0.84 GRM7 (0.40) GRM7GRM4
SCHEMBL10338402 0.83 CHRM1 (0.42) GRM7GRM4
Flumioxazin SCHEMBL7581438 0.81 MEN1 (0.33)
SCHEMBL10531135 0.81 GRM7 (0.40) GRM7GRM4
Flumioxazin SCHEMBL28092319 0.81 CHRM5 (0.35)
Flumioxazin SCHEMBL7580601 0.81 GRM7 (0.35) GRM7GRM4GRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0263299-B1 BENZOXAZINES NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1990-11-07 EP claimed
US-4804394-A Benzoxazines and use as herbicides NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1989-02-14 US claimed
EP-0263299-A1 Benzoxazines NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1988-04-13 EP claimed
JP-63277675-A None JP disclosed
JP-63068587-A None JP disclosed
EP-0263299-B1 BENZOXAZINES NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1990-11-07 EP disclosed
US-4804394-A Benzoxazines and use as herbicides NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1989-02-14 US disclosed
US-4798620-A Benzoxazines and herbicidal use NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1989-01-17 US disclosed
EP-0290863-A2 Benzoxazine derivative, process and intermediates for its preparation and its use as herbicide NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1988-11-17 EP disclosed
JP-S63277675-A NOVEL BENZOXAZINES NIPPON TOKUSHU NOYAKU SEIZO KK 1988-11-15 JP disclosed
EP-0263299-A1 Benzoxazines NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1988-04-13 EP disclosed
JP-S6368587-A TETRAHYDROPHTHALIMIDES AND HERBICIDE NIPPON TOKUSHU NOYAKU SEIZO KK 1988-03-28 JP disclosed