Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
| ▸ | NR1I2 | O75469 | 5/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | ALB | P02768 | 1/20 | 0.44 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.44 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.44 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 2/20 | 0.43 |
| ▸ | PGR | P06401 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | APEX1 | P27695 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9365530 | 1.00 | PTGS1 (0.48) | PTGS1ABCB11PDE4DNR1I2HTR2C | |
| SCHEMBL9622693 | 1.00 | PTGS1 (0.48) | PTGS1ABCB11PDE4DNR1I2HTR2C | |
| SCHEMBL9365535 | 1.00 | PTGS1 (0.48) | PTGS1ABCB11PDE4DNR1I2HTR2C | |
| SCHEMBL9622690 | 1.00 | PTGS1 (0.48) | PTGS1ABCB11PDE4DNR1I2HTR2C | |
| SCHEMBL10366301 | 0.94 | PTGS1 (0.48) | PTGS1ABCB11PDE4DNR1I2HTR2C | |
| SCHEMBL9623029 | 0.94 | PTGS1 (0.48) | PTGS1ABCB11PDE4DNR1I2HTR2C | |
| SCHEMBL9622995 | 0.94 | PTGS1 (0.48) | PTGS1ABCB11PDE4DNR1I2HTR2C | |
| SCHEMBL9361767 | 0.94 | PTGS1 (0.53) | PTGS1ABCB11PDE4DNR1I2HTR2C | |
| SCHEMBL9623563 | 0.94 | PTGS1 (0.53) | PTGS1ABCB11PDE4DNR1I2HTR2C | |
| SCHEMBL9623560 | 0.94 | PTGS1 (0.53) | PTGS1ABCB11PDE4DNR1I2HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0121244-B1 | CEPHALOSPORIN DERIVATIVES | Bristol-Myers Company (US) | 1990-09-12 | — | — | EP | disclosed |
| US-4525473-A | BACTERICIDES | BRISTOL-MYERS COMPANY (US) | 1985-06-25 | — | — | US | disclosed |
| EP-0121244-A2 | Cephalosporin derivatives | Bristol-Myers Company (US) | 1984-10-10 | — | — | EP | disclosed |
| US-4406899-A | Cephalosporins | BRISTOL-MYERS COMPANY (US) | 1983-09-27 | — | — | US | disclosed |