Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Tert-Butylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tert-Butylamine SCHEMBL10837638 | 1.00 | FNTA (0.41) | FNTAFNTBCA1CA2CA4 | |
| SCHEMBL3182370 | 0.89 | FNTA (0.47) | FNTAFNTBCA1CA2CA4 | |
| SCHEMBL28205206 | 0.89 | FNTA (0.47) | FNTAFNTBCA1CA2CA4 | |
| Ammonia Solution, Strong SCHEMBL9638545 | 0.86 | FNTA (0.46) | FNTAFNTBCA1CA2CA4 | |
| SCHEMBL27257292 | 0.86 | FNTA (0.46) | FNTAFNTBCA1CA2CA4 | |
| Fluoride SCHEMBL10492292 | 0.86 | FNTA (0.46) | FNTAFNTBCA1CA2CA4 | |
| Trimethylammonium SCHEMBL10838652 | 0.82 | FNTA (0.43) | FNTAFNTBCA1CA2CA4 | |
| SCHEMBL28257083 | 0.80 | FNTA (0.42) | FNTAFNTBCA1CA2CA4 | |
| SCHEMBL10969272 | 0.77 | FNTA (0.40) | FNTAFNTBCA1CA2CA4 | |
| N,N-Dimethylethanaminium SCHEMBL9638521 | 0.77 | FNTA (0.40) | FNTAFNTBCA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0155634-B1 | PROCESS FOR THE PREPARATION OF 6-METHYL-3,4-DIHYDRO-1,2,3-OXATHIAZIN-4-ONE 2,2-DIOXIDE AND OF ITS NON-TOXIC SALTS, AS WELL AS OF ACETOACETAMIDE-N-SULFONIC ACID OCCURRING AS AN INTERMEDIARY IN THIS PROCESS, AND ITS SALTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-06-13 | — | — | EP | disclosed |