Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10374885 | 0.99 | PDE3B (0.67) | PDE3BPDE3A | |
| SCHEMBL10375856 | 0.97 | PDE3B (0.70) | PDE3BPDE3A | |
| SCHEMBL10753769 | 0.91 | PDE3B (0.66) | PDE3BPDE3A | |
| SCHEMBL10374701 | 0.91 | PDE3B (0.66) | PDE3BPDE3A | |
| SCHEMBL10376783 | 0.90 | PDE3B (0.67) | PDE3BPDE3A | |
| SCHEMBL10751576 | 0.90 | PDE3B (0.67) | PDE3BPDE3A | |
| SCHEMBL10375086 | 0.89 | PDE3B (0.64) | PDE3BPDE3A | |
| SCHEMBL10375736 | 0.89 | PDE3B (0.64) | PDE3BPDE3A | |
| SCHEMBL10374690 | 0.89 | PDE3B (0.66) | PDE3BPDE3A | |
| SCHEMBL10375725 | 0.89 | PDE3B (0.66) | PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0116948-B1 | (2-OXO-1,2,3,5-TETRAHYDROIMIDAZO-(2,1-B)QUINAZOLINYL)-OXYALKYL-AMIDES | SYNTEX (U.S.A.) INC. (US) | 1990-01-03 | — | — | EP | disclosed |
| US-4663320-A | ANTITUMOR AGENTS, ANTICOAGULANTS | SYNTEX (U.S.A.) INC. (US) | 1987-05-05 | — | — | US | disclosed |
| US-4551459-A | Method of treating heart failure using (2-oxo-1,2,3,5-tetrahydroimidazo-[2,1-b]quinazolinyl)oxyalkylamides | SYNTEX (U.S.A.) INC. (US) | 1985-11-05 | — | — | US | disclosed |
| US-4490371-A | ANTICOAGULANTS, PHOSPHODIESTERASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1984-12-25 | — | — | US | disclosed |
| EP-0116948-A2 | (2-Oxo-1,2,3,5-tetrahydroimidazo-(2,1-b)quinazolinyl)-oxyalkyl-amides | SYNTEX (U.S.A.) INC. (US) | 1984-08-29 | — | — | EP | disclosed |