Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6648870 | 0.78 | NAMPT (0.43) | KMT2AHSD17B10LMNAALDH1A1 | |
| SCHEMBL7697845 | 0.77 | ABCB1 (0.46) | HTTTDP1LMNACYP2D6GRIN2B | |
| SCHEMBL9197472 | 0.77 | KMT2A (0.56) | KMT2AMEN1HTTGFERHSD17B10 | |
| SCHEMBL28758529 | 0.76 | ALPI (0.47) | — | |
| SCHEMBL6236586 | 0.76 | TDP1 (0.54) | KMT2APOLBTDP1LMNACYP3A4 | |
| SCHEMBL8782175 | 0.75 | KMT2A (0.54) | KMT2AMEN1HTTGFERHSD17B10 | |
| SCHEMBL9663709 | 0.75 | CYP19A1 (0.61) | KMT2AMEN1HTTGFERHSD17B10 | |
| SCHEMBL10377969 | 0.75 | TSHR (0.39) | TDP1LMNAALDH1A1L3MBTL1TSHR | |
| Carbamic Acid SCHEMBL9362680 | 0.75 | KMT2A (0.57) | KMT2AMEN1HTTGFERHSD17B10 | |
| SCHEMBL10377649 | 0.75 | TSHR (0.39) | KMT2AHTTGFERCYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0189045-B1 | PYRIDOPYRIMIDINES, DIFFERENT PROCESSES FOR THEIR PREPARATION AS WELL AS THEIR USE AS MEDICAMENTS | BAYER AG (DE) | 1990-02-14 | — | — | EP | disclosed |