Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | MEN1 | O00255 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.55 |
| ▸ | MAOA | P21397 | 4/20 | 0.53 |
| ▸ | MAOB | P27338 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10377341 | 1.00 | NR1H4 (0.68) | NR1H4KMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL4778481 | 0.87 | KMT2A (0.61) | NR1H4KMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL4778485 | 0.87 | KMT2A (0.61) | NR1H4KMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL9297690 | 0.87 | KMT2A (0.61) | NR1H4KMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL10376667 | 0.86 | NR1H4 (0.57) | NR1H4KMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL10376666 | 0.86 | NR1H4 (0.57) | NR1H4KMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL6041621 | 0.81 | NR1H4 (1.00) | NR1H4KMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL5860473 | 0.80 | MEN1 (0.72) | NR1H4KMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL10375338 | 0.79 | ATM (0.59) | NR1H4KMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL10375339 | 0.79 | ATM (0.59) | NR1H4KMT2AMAPTMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0169712-B1 | NEW PYRIMIDINE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND COMPOSITION CONTAINING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-12-12 | — | — | EP | disclosed |
| US-4698340-A | TREATMENT OF CEREBROVASCULAR DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-10-06 | — | — | US | disclosed |