SCHEMBL10377486

SCHEMBL10377486

NC1C=CC=NC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10066304 0.72
SCHEMBL17900003 0.68
SCHEMBL14136442 0.67
SCHEMBL14406056 0.67
SCHEMBL16681899 0.67
SCHEMBL19250313 0.67
SCHEMBL806454 0.67
SCHEMBL189638 0.64
SCHEMBL1017724 0.64
SCHEMBL20403372 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0244713-B1 3-AMINO-DIHYDROPYRIDINES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS BAYER AG (DE) 1990-08-16 EP claimed
US-4772611-A CARDIOACTIVE BAYER AKTIENGESELLSCHAFT (DE) 1988-09-20 US claimed
EP-0244713-A2 3-Amino-dihydropyridines, process for their preparation and their use as medicaments BAYER AG (DE) 1987-11-11 EP claimed
EP-4282933-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE Samsung Electronics Co., Ltd. (KR) 2023-11-29 EP disclosed
EP-4236659-A1 LIGHT-EMITTING DEVICE, ELECTRONIC APPARATUS INCLUDING THE LIGHTEMITTING DEVICE, AND MIXTURE Samsung Electronics Co., Ltd. (KR) 2023-08-30 EP disclosed
EP-4236660-A1 LIGHT-EMITTING DEVICE AND ELECTRONIC APPARATUS INCLUDING THE SAME Samsung Electronics Co., Ltd. (KR) 2023-08-30 EP disclosed
EP-3351543-A1 1-(QUINOLIN-4-YL)-3-(6-(TRIFLUOROMETHYL)-PYRIDIN-2-YL)UREA AND 1-(QUINOLIN-4-YL)-3-(6-(TRIFLUOROMETHYL)-PYRAZINE-2-YL)UREA DERIVATIVES AS GLYCOGEN SYNTHASE KINASE 3 (GSK-3) INHIBITORS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES AbbVie Deutschland GmbH & Co. KG (DE) 2018-07-25 EP disclosed
CN-107849015-A benzimidazole derivatives as PAD4 inhibitors 葛兰素知识产权发展有限公司 2018-03-27 CN disclosed
EP-1805181-B1 PURINE DERIVATIVES FOR USE AS ADENOSIN A-2A RECEPTOR AGONISTS NOVARTIS AG (CH) 2012-08-29 EP disclosed
EP-0244713-B1 3-AMINO-DIHYDROPYRIDINES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS BAYER AG (DE) 1990-08-16 EP disclosed
EP-0244713-B1 3-AMINO-DIHYDROPYRIDINES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS BAYER AG (DE) 1990-08-16 EP disclosed
US-4772611-A CARDIOACTIVE BAYER AKTIENGESELLSCHAFT (DE) 1988-09-20 US disclosed
US-4772611-A CARDIOACTIVE BAYER AKTIENGESELLSCHAFT (DE) 1988-09-20 US disclosed
EP-0244713-A2 3-Amino-dihydropyridines, process for their preparation and their use as medicaments BAYER AG (DE) 1987-11-11 EP disclosed
EP-0244713-A2 3-Amino-dihydropyridines, process for their preparation and their use as medicaments BAYER AG (DE) 1987-11-11 EP disclosed