Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.30 |
| ▸ | HTT | P42858 | 2/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.30 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | STAT3 | P40763 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10378037 | 1.00 | CHRM4 (0.32) | CHRM4SMN1; SMN2TP53MAPK1HTT | |
| SCHEMBL10378454 | 0.87 | CHRM4 (0.33) | CHRM4SMN1; SMN2TP53MAPK1BRD4 | |
| SCHEMBL10378455 | 0.87 | CHRM4 (0.33) | CHRM4SMN1; SMN2TP53MAPK1BRD4 | |
| SCHEMBL11101848 | 0.86 | MAPT (0.39) | CHRM4SMN1; SMN2MAPK1KDM4EALDH1A1 | |
| SCHEMBL10378009 | 0.85 | S1PR2 (0.35) | CHRM4SMN1; SMN2TP53MAPK1BRD4 | |
| SCHEMBL11107034 | 0.83 | PDE5A (0.38) | CHRM4SMN1; SMN2MAPK1HTTBRD4 | |
| SCHEMBL11108006 | 0.81 | MAPT (0.39) | CHRM4SMN1; SMN2MAPK1HTTKDM4E | |
| SCHEMBL9774853 | 0.81 | TP53 (0.37) | CHRM4SMN1; SMN2TP53MAPK1HTT | |
| SCHEMBL10378609 | 0.80 | TP53 (0.37) | CHRM4SMN1; SMN2TP53MAPK1HTT | |
| Hydrochloric Acid SCHEMBL10376554 | 0.80 | NPC1 (0.37) | CHRM4SMN1; SMN2TP53MAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0196524-B1 | PHENOXYALKYLAMINOPYRIMIDINE DERIVATIVES, THEIR PREPARATION AND INSECTICIDAL AND ACARICIDAL COMPOSITIONS CONTAINING THEM | SANKYO COMPANY LIMITED (JP) | 1990-03-07 | — | — | EP | disclosed |
| US-4845097-A | AGRICULTURE | SANKYO COMPANY LIMITED (JP) | 1989-07-04 | — | — | US | disclosed |
| EP-0196524-A2 | Phenoxyalkylaminopyrimidine derivatives, their preparation and insecticidal and acaricidal compositions containing them | SANKYO COMPANY LIMITED (JP) | 1986-10-08 | — | — | EP | disclosed |