Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | F7 | P08709 | 2/20 | 0.44 |
| ▸ | F3 | P13726 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 4/20 | 0.42 |
| ▸ | PPARA | Q07869 | 4/20 | 0.42 |
| ▸ | TERT | O14746 | 3/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | FABP4 | P15090 | 2/20 | 0.40 |
| ▸ | FAAH | O00519 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PPARD | Q03181 | 2/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10310662 | 1.00 | MAPT (0.44) | MAPTF7F3PPARGPPARA | |
| SCHEMBL1883791 | 1.00 | MAPT (0.44) | MAPTF7F3PPARGPPARA | |
| SCHEMBL15367136 | 0.93 | PPARG (0.51) | MAPTF7F3PPARGPPARA | |
| SCHEMBL31017075 | 0.93 | PPARG (0.51) | MAPTF7F3PPARGPPARA | |
| SCHEMBL7133496 | 0.93 | PPARG (0.51) | MAPTF7F3PPARGPPARA | |
| SCHEMBL15367138 | 0.93 | PPARG (0.51) | MAPTF7F3PPARGPPARA | |
| SCHEMBL7133502 | 0.93 | PPARG (0.51) | MAPTF7F3PPARGPPARA | |
| SCHEMBL13969979 | 0.90 | MAPT (0.44) | MAPTF7F3PPARGPPARA | |
| SCHEMBL4582615 | 0.89 | MAPT (0.42) | MAPTF7F3PPARGPPARA | |
| SCHEMBL4938624 | 0.89 | MAPT (0.46) | MAPTF7F3PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990002740-A1 | 2-OXA-BICYCLO[2.2.1]HEPTANE DERIVATIVES AND DRUGS CONTAINING SAID COMPOUNDS | SCHERING AKTIENGESELLSCHAFT BERLIN UND BERGKAMEN (DE) | 1990-03-22 | — | — | WO | disclosed |
| EP-0358290-A1 | 2-Oxa-bicyclo[2.2.1]heptane derivatives and medicines containing these compounds | SCHERING AKTIENGESELLSCHAFT (DE) | 1990-03-14 | — | — | EP | disclosed |