Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | GALR3 | O60755 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | NR2F2 | P24468 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PDE11A | Q9HCR9 | 3/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10376504 | 0.90 | SMN1; SMN2 (0.38) | SMN1; SMN2MAPK1MEN1STAT3KMT2A | |
| SCHEMBL11108006 | 0.90 | MAPT (0.39) | SMN1; SMN2MAPK1MEN1STAT3KMT2A | |
| SCHEMBL10378110 | 0.89 | SMN1; SMN2 (0.38) | SMN1; SMN2MAPK1MEN1STAT3KMT2A | |
| SCHEMBL11103934 | 0.88 | SMN1; SMN2 (0.39) | SMN1; SMN2MAPK1MEN1STAT3KMT2A | |
| SCHEMBL11107034 | 0.87 | PDE5A (0.38) | SMN1; SMN2MAPK1MEN1STAT3KMT2A | |
| SCHEMBL11107563 | 0.87 | S1PR2 (0.40) | SMN1; SMN2MAPK1MEN1STAT3KMT2A | |
| SCHEMBL11290159 | 0.87 | SMN1; SMN2 (0.36) | SMN1; SMN2MAPK1MEN1STAT3KMT2A | |
| SCHEMBL9774853 | 0.87 | TP53 (0.37) | SMN1; SMN2MAPK1MEN1STAT3KMT2A | |
| SCHEMBL10377982 | 0.87 | MAPT (0.39) | SMN1; SMN2MAPK1MEN1STAT3KMT2A | |
| SCHEMBL11103568 | 0.87 | CHRM4 (0.39) | SMN1; SMN2MAPK1MEN1STAT3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0196524-B1 | PHENOXYALKYLAMINOPYRIMIDINE DERIVATIVES, THEIR PREPARATION AND INSECTICIDAL AND ACARICIDAL COMPOSITIONS CONTAINING THEM | SANKYO COMPANY LIMITED (JP) | 1990-03-07 | — | — | EP | disclosed |
| US-4845097-A | AGRICULTURE | SANKYO COMPANY LIMITED (JP) | 1989-07-04 | — | — | US | disclosed |
| EP-0196524-A2 | Phenoxyalkylaminopyrimidine derivatives, their preparation and insecticidal and acaricidal compositions containing them | SANKYO COMPANY LIMITED (JP) | 1986-10-08 | — | — | EP | disclosed |