Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 7/20 | 0.72 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.72 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.72 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.72 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.72 |
| ▸ | CA12 | O43570 | 1/20 | 0.66 |
| ▸ | CA1 | P00915 | 1/20 | 0.66 |
| ▸ | CA2 | P00918 | 1/20 | 0.66 |
| ▸ | CA7 | P43166 | 1/20 | 0.66 |
| ▸ | CA9 | Q16790 | 1/20 | 0.66 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.66 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | CNR2 | P34972 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31125321 | 1.00 | ESR1 (0.72) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL31125318 | 1.00 | ESR1 (0.72) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL1040996 | 1.00 | ESR1 (0.72) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL1042180 | 1.00 | ESR1 (0.72) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL1042703 | 1.00 | ESR1 (0.72) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL1041010 | 1.00 | ESR1 (0.72) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL11131748 | 1.00 | ESR1 (0.72) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL4960394 | 1.00 | ESR1 (0.72) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL1039666 | 1.00 | ESR1 (0.72) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL31125336 | 1.00 | ESR1 (0.72) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095996-B1 | Thermochromic solid having reversibly invisible/visible construction enclosed therein | PILOT INK CO LTD (JP) | 2011-01-26 | — | — | EP | disclosed |
| US-6468088-B1 | Solid having reversibly invisible/visible thermochromic construction enclosed therein | THE PILOT INK CO., LTD. (JP) | 2002-10-22 | — | — | US | disclosed |
| EP-1095996-A1 | Thermochromic solid having reversibly invisible/visible construction enclosed therein | THE PILOT INK CO., LTD. (JP) | 2001-05-02 | — | — | EP | disclosed |