Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 1/20 | 0.45 |
| ▸ | MTOR | P42345 | 1/20 | 0.45 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.45 |
| ▸ | RPS6KB2 | Q9UBS0 | 2/20 | 0.43 |
| ▸ | MGMT | P16455 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GBA1 | P04062 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.36 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5998120 | 0.84 | PIK3CA (0.46) | PIK3CAMTORPIK3CGRPS6KB2MGMT | |
| SCHEMBL540122 | 0.82 | MGMT (0.58) | PIK3CAMTORPIK3CGMGMTADORA2A | |
| SCHEMBL1029868 | 0.77 | SMN1; SMN2 (0.51) | PIK3CAMTORPIK3CGSMN1; SMN2CHEK1 | |
| SCHEMBL10379222 | 0.77 | PIK3CA (0.57) | PIK3CAMTORPIK3CGRPS6KB2MGMT | |
| SCHEMBL16266000 | 0.74 | MGMT (0.52) | PIK3CAMTORPIK3CGMGMTADORA2A | |
| SCHEMBL5997151 | 0.71 | PIK3CA (0.57) | PIK3CAMTORPIK3CGMGMTADORA2A | |
| SCHEMBL6783434 | 0.70 | GRIA1 (0.59) | PIK3CAMTORPIK3CGADORA2AADORA1 | |
| Xanthine SCHEMBL9443819 | 0.68 | GDA (0.44) | ADORA2AADORA1ADORA3LMNAPDPK1 | |
| SCHEMBL539271 | 0.68 | BRD4 (0.46) | PIK3CAMTORPIK3CGSMN1; SMN2CHEK1 | |
| SCHEMBL29453250 | 0.68 | BRD4 (0.46) | PIK3CAMTORPIK3CGSMN1; SMN2CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990006312-A1 | 2',3'-DIDEOXYRIBOFURANOSIDES AND PROCESS FOR PRODUCING THEM | INSTITUT FÜR MOLEKULARBIOLOGIE UND ANALYTIK (IMA) GMBH (DE) | 1990-06-14 | — | — | WO | disclosed |