Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 15/20 | 0.51 |
| ▸ | CYP17A1 | P05093 | 6/20 | 0.51 |
| ▸ | CYP21A2 | P08686 | 1/20 | 0.51 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9817484 | 0.85 | CYP19A1 (0.45) | CYP19A1OR51E2 | |
| SCHEMBL9817311 | 0.84 | CYP19A1 (0.50) | CYP19A1OR51E2 | |
| SCHEMBL9817226 | 0.84 | CYP19A1 (0.41) | CYP19A1OR51E2 | |
| SCHEMBL9817206 | 0.83 | CYP19A1 (0.52) | CYP19A1OR51E2 | |
| SCHEMBL8807999 | 0.83 | CYP19A1 (0.48) | CYP19A1OR51E2 | |
| SCHEMBL8806253 | 0.82 | CYP19A1 (0.50) | CYP19A1OR51E2 | |
| SCHEMBL9817312 | 0.82 | CYP19A1 (0.45) | CYP19A1OR51E2 | |
| SCHEMBL9817199 | 0.82 | CYP19A1 (0.43) | CYP19A1OR51E2 | |
| SCHEMBL9817434 | 0.82 | CYP19A1 (0.43) | CYP19A1OR51E2 | |
| SCHEMBL9817376 | 0.82 | CYP19A1 (0.44) | CYP19A1OR51E2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990014354-A1 | STEROIDS WITH A 9α-HYDROXY-19,11β BRIDGE, THEIR PREPARATION AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM | SCHERING AKTIENGESELLSCHAFT BERLIN UND BERGKAMEN (DE) | 1990-11-29 | — | — | WO | disclosed |