Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 3/20 | 0.47 |
| ▸ | RARA | P10276 | 1/20 | 0.47 |
| ▸ | RARG | P13631 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 2/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10382229 | 0.99 | RARB (0.49) | RARBRARARARGPPARAPPARG | |
| SCHEMBL10383062 | 0.96 | RARB (0.48) | RARBRARARARGPPARAPPARG | |
| SCHEMBL10383006 | 0.95 | RARB (0.50) | RARBRARARARGPPARAPPARG | |
| SCHEMBL10382994 | 0.95 | RARB (0.50) | RARBRARARARGPPARAPPARG | |
| SCHEMBL10381650 | 0.95 | RARB (0.50) | RARBRARARARGPPARAPPARG | |
| SCHEMBL10381822 | 0.95 | RARB (0.50) | RARBRARARARGPPARAPPARG | |
| SCHEMBL10381666 | 0.95 | RARB (0.50) | RARBRARARARGPPARAPPARG | |
| SCHEMBL10381821 | 0.95 | RARB (0.44) | RARBRARARARGPPARAPPARG | |
| SCHEMBL10381648 | 0.95 | RARB (0.50) | RARBRARARARGPPARAPPARG | |
| SCHEMBL10382610 | 0.95 | RARB (0.50) | RARBRARARARGPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4897216-A | 2,3-difluorophenol derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1990-01-30 | — | — | US | disclosed |