Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 13/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL10383123 | 0.92 | CHRNA7 (0.46) | CHRNA7ACHEFYNSERPINE1 | |
| Sulfuric Acid SCHEMBL10383124 | 0.91 | CHRNA7 (0.45) | CHRNA7ACHEFYNSERPINE1 | |
| Sulfuric Acid SCHEMBL10384420 | 0.91 | CHRNA7 (0.45) | CHRNA7ACHEFYNSERPINE1 | |
| SCHEMBL10383657 | 0.86 | CHRNA7 (0.52) | CHRNA7ACHEFYN | |
| Iodide SCHEMBL10383712 | 0.84 | CHRNA7 (0.51) | CHRNA7FYN | |
| Hydrochloric Acid SCHEMBL10383708 | 0.84 | CHRNA7 (0.51) | CHRNA7ACHEFYN | |
| Bromide SCHEMBL10383382 | 0.84 | CHRNA7 (0.55) | CHRNA7ACHEFYN | |
| Sulfuric Acid SCHEMBL10383288 | 0.82 | CHRNA7 (0.64) | CHRNA7ACHELMNA | |
| Sulfuric Acid SCHEMBL10384413 | 0.81 | CHRNA7 (0.67) | CHRNA7ACHELMNA | |
| Sulfuric Acid SCHEMBL10383287 | 0.80 | CHRNA7 (0.66) | CHRNA7ACHELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4958029-A | Process for the production of isoindoline derivatives, novel intermediates and process for their production | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1990-09-18 | — | — | US | disclosed |
| EP-0275064-A2 | Process for the production of isoindoline derivatives, novel intermediates and process for their production | Banyu Pharmaceutical Co., Ltd. (JP) | 1988-07-20 | — | — | EP | disclosed |