Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | MPO | P05164 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | BLM | P54132 | 1/20 | 0.62 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.62 |
| ▸ | HTR2A | P28223 | 2/20 | 0.60 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.60 |
| ▸ | HTR1A | P08908 | 1/20 | 0.60 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.60 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.60 |
| ▸ | HTR1D | P28221 | 1/20 | 0.60 |
| ▸ | HTR1B | P28222 | 1/20 | 0.60 |
| ▸ | HTR2C | P28335 | 1/20 | 0.60 |
| ▸ | HTR1E | P28566 | 1/20 | 0.60 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tryptophan SCHEMBL9331925 | 0.81 | KDM4E (0.89) | MAPTKDM4EMEN1KMT2ALMNA | |
| Dl-Tryptophan SCHEMBL27639189 | 0.81 | KDM4E (0.89) | MAPTKDM4EMEN1KMT2ALMNA | |
| SCHEMBL10384697 | 0.81 | HTR2A (0.60) | MAPTKDM4EMEN1KMT2ALMNA | |
| Tryptophan SCHEMBL5367288 | 0.80 | KDM4E (0.86) | MAPTKDM4EMEN1KMT2ALMNA | |
| Dl-Tryptophan SCHEMBL28597291 | 0.80 | KDM4E (0.86) | MAPTKDM4EMEN1KMT2ALMNA | |
| Dl-Tryptophan SCHEMBL5367284 | 0.80 | KDM4E (0.86) | MAPTKDM4EMEN1KMT2ALMNA | |
| D-Tryptophan SCHEMBL5356575 | 0.80 | KDM4E (0.86) | MAPTKDM4EMEN1KMT2ALMNA | |
| SCHEMBL10384622 | 0.79 | HTR2A (0.58) | MAPTKDM4EMEN1KMT2ALMNA | |
| SCHEMBL28389774 | 0.79 | MAPT (0.58) | MAPTKDM4EMEN1KMT2ALMNA | |
| SCHEMBL29941662 | 0.79 | HTR2A (0.70) | MAPTKDM4EMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4946833-A | ANTITUMOR AGENTS | ADIR ET CIE (FR) | 1990-08-07 | — | — | US | disclosed |