SCHEMBL103847

SCHEMBL103847

N#Cc1ccccc1C(F)(F)F

nearest known ligand 0.59

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
AR P10275 17/20 0.59
SLC22A12 Q96S37 3/20 0.51
PGR P06401 3/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30794742 1.00 AR (0.59) ARSLC22A12PGR
Hydrochloric Acid SCHEMBL30636352 0.98 AR (0.58) ARSLC22A12PGR
Hydrochloric Acid SCHEMBL22117993 0.98 AR (0.58) ARSLC22A12PGR
Hydrochloric Acid SCHEMBL3872539 0.98 AR (0.58) ARSLC22A12PGR
Bromide SCHEMBL30389929 0.98 AR (0.58) ARSLC22A12PGR
Ammonia Solution, Strong SCHEMBL27656720 0.98 AR (0.58) ARSLC22A12PGR
Hydrogen Sulfide SCHEMBL28182413 0.94 AR (0.54) ARSLC22A12PGR
SCHEMBL28311735 0.92 AR (0.53) ARSLC22A12PGR
Isothiocyanate SCHEMBL28855999 0.90 AR (0.51) ARSLC22A12PGR
SCHEMBL28485189 0.88 SLC22A12 (0.55) ARSLC22A12PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1162 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260109699-A1 AZOLE DERIVATIVES AS SHP2 INHIBITORS IRBM S.P.A. (IT) 2026-04-23 US claimed
EP-3131588-B1 IMIDE-BASED MODULATORS OF PROTEOLYSIS AND ASSOCIATED METHODS OF USE ARVINAS OPERATIONS INC (US) 2025-11-05 EP claimed
EP-4594324-A1 AZOLE DERIVATIVES AS SHP2 INHIBITORS IRBM S.P.A. (IT) 2025-08-06 EP claimed
EP-4543870-A1 NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS F. Hoffmann-La Roche AG (CH) 2025-04-30 EP claimed
CN-119654312-A Substituted tetrazolyl compounds useful as T cell activators 百时美施贵宝公司 2025-03-18 CN claimed
CN-119591582-A Imide-based proteolytic modulators and related methods of use 阿尔维纳斯运营股份有限公司 2025-03-11 CN claimed
CN-119490427-A Preparation method of 2-trifluoromethyl benzamide 宁夏忠同生物科技有限公司 2025-02-21 CN claimed
CN-115677522-B Preparation method of o-trifluoromethyl benzamide and intermediate thereof 浙江巍华新材料股份有限公司 2025-02-14 CN claimed
EP-3135669-B1 OXAZOLIDINE-BASED COMPOUND AND SELECTIVE ANDROGEN RECEPTOR AGONIST COMPRISING SAME DONG A ST CO LTD (KR) 2024-08-28 EP claimed
WO-2024068976-A1 AZOLE DERIVATIVES AS SHP2 INHIBITORS IRBM S.P.A. (IT) 2024-04-04 WO claimed
CN-1127753-A New imidazolidines substituted by a heterocycle, their preparation process and intermediates, their use as medicaments NAD the pharmaceutical compositions containing them ROUSSEL UCLAF (FR) 1996-07-31 CN claimed
EP-0704448-A1 Heterocyclic substituted imidazolidines, process and intermediates for their preparation, their use as medicaments and pharmaceutical compositions containing them ROUSSEL UCLAF (FR) 1996-04-03 EP claimed
WO-1995018794-A1 NOVEL OPTIONALLY SUBSTITUTED PHENYLIMIDAZOLIDINES, INTERMEDIATES AND PROCESS FOR THEIR PREPARATION, THEIR USE AS DRUGS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM ROUSSEL UCLAF (FR) 1995-07-13 WO claimed
EP-0578516-A1 Optionally substituted phenylimidazolidins, process for their preparation, their use as medicaments and the pharmaceutical compositions containing them ROUSSEL UCLAF (FR) 1994-01-12 EP claimed
CN-1063102-A New phenylimidazolidines,, prepare they method, they are as the application of medicine and the pharmaceutical composition that contains them ROUSSEL UCLAF (FR) 1992-07-29 CN claimed
US-5126497-A Catalyst and process for the preparation of trifluoromethyltoluenes OCCIDENTAL CHEMICAL CORPORATION (US) 1992-06-30 US claimed
US-5084478-A Antiandrogens for treatment of prostatic disease, acne, hirsutism or seborrhoea IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1992-01-28 US claimed
US-4808746-A Preparation of trifluoromethylbenzonitrile from trifluoromethylbenzaldehyde CENTRAL GLASS COMPANY, LIMITED (JP) 1989-02-28 US claimed
EP-0097357-B1 PROCESS FOR PREPARING TRIFLUOROMETHYLBENZENE DERIVATIVES Daikin Kogyo Co., Ltd. (JP) 1986-01-08 EP claimed
US-4493800-A REACTING A TRIFLUOROMETHYLHALOGENOBENZENE WITH COPPER CYANIDE DAIKIN KOGYO CO., LTD. (JP) 1985-01-15 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260109699-A1 AZOLE DERIVATIVES AS SHP2 INHIBITORS PTPN1, PTPN5, PTPN3 AR 1177/4885SLC22A12 4333/4885PGR 2326/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.