Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 12/20 | 1.00 |
| ▸ | PTGS2 | P35354 | 12/20 | 1.00 |
| ▸ | ALOX5 | P09917 | 11/20 | 0.62 |
| ▸ | TTR | P02766 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10799253 | 1.00 | PTGS1 (1.00) | PTGS1PTGS2ALOX5TTRNPC1 | |
| SCHEMBL709945 | 0.90 | PTGS1 (0.82) | PTGS1PTGS2ALOX5TTRNPC1 | |
| SCHEMBL709946 | 0.90 | PTGS1 (0.82) | PTGS1PTGS2ALOX5TTRNPC1 | |
| SCHEMBL10385860 | 0.87 | PTGS1 (0.76) | PTGS1PTGS2ALOX5TTRNPC1 | |
| SCHEMBL10385608 | 0.85 | PTGS1 (0.74) | PTGS1PTGS2ALOX5TTRNPC1 | |
| SCHEMBL17678714 | 0.83 | PTGS1 (0.71) | PTGS1PTGS2NPC1RAB9AMEN1 | |
| SCHEMBL10385837 | 0.83 | PTGS1 (0.70) | PTGS1PTGS2ALOX5TTRNPC1 | |
| SCHEMBL10502794 | 0.82 | PTGS1 (0.70) | PTGS1PTGS2ALOX5TTR | |
| SCHEMBL10505097 | 0.82 | PTGS1 (0.70) | PTGS1PTGS2ALOX5TTR | |
| SCHEMBL9605437 | 0.80 | PTGS1 (0.67) | PTGS1PTGS2ALOX5TTRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4945138-A | Styrylaza vinyl esters | THE DOW CHEMICAL COMPANY (US) | 1990-07-31 | — | — | US | disclosed |
| US-4883844-A | FROM AROMATIC ALDEHYDE AND SUBSTITUTED PYRIDINE | THE DOW CHEMICAL COMPANY (US) | 1989-11-28 | — | — | US | disclosed |
| US-4851483-A | FROM EPOXIDIZED HYDROXYSTYRYLAZA COMPOUNDS DERIVED FROM AROMATIC HYDROXYALDEHYDES AND METHYLATED PYRIDINES OR PYRAZINES | THE DOW CHEMICAL COMPANY (US) | 1989-07-25 | — | — | US | disclosed |
| EP-0212095-A1 | Thermosettable compounds prepared from monohydroxy aromatic aldehydes and methylated pyridines or pyrazines | THE DOW CHEMICAL COMPANY (US) | 1987-03-04 | — | — | EP | disclosed |
| US-4600767-A | Thermostable hydroxystyrylaza compounds | THE DOW CHEMICAL COMPANY (US) | 1986-07-15 | — | — | US | disclosed |