Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | APAF1 | O14727 | 1/20 | 0.44 |
| ▸ | GRK2 | P25098 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10387956 | 0.82 | HPGD (0.57) | HTTHPGDPOLBCA1CA2 | |
| SCHEMBL10387942 | 0.79 | POLB (0.65) | HTTPOLBCA1CA2NPC1 | |
| SCHEMBL10388861 | 0.78 | HPGD (0.48) | HTTHPGDPOLBNPC1RAB9A | |
| SCHEMBL10387959 | 0.78 | NPC1 (0.65) | POLBCA1CA2NPC1RAB9A | |
| SCHEMBL10388432 | 0.76 | CA1 (0.72) | HTTHPGDPOLBCA1CA2 | |
| SCHEMBL10389730 | 0.74 | CYP1A2 (0.63) | HPGDPOLBCA1CA2NPC1 | |
| SCHEMBL10389746 | 0.74 | HPGD (0.57) | HTTHPGDPOLBCA1CA2 | |
| SCHEMBL10387957 | 0.72 | POLB (0.62) | HTTHPGDPOLBCA1CA2 | |
| SCHEMBL16950775 | 0.72 | HSD17B10 (0.40) | HTTCA1CA2NPC1RAB9A | |
| SCHEMBL16950780 | 0.71 | HSD17B10 (0.39) | CA1CA2RAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4906277-A | Isoxazoline derivatives and plant growth regulators | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1990-03-06 | — | — | US | disclosed |
| US-4889551-A | Isoxazoline derivatives and plant growth regulators | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1989-12-26 | — | — | US | disclosed |