Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.63 |
| ▸ | RAB9A | P51151 | 4/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.63 |
| ▸ | CASP3 | P42574 | 2/20 | 0.63 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.63 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.63 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | ATM | Q13315 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.57 |
| ▸ | RELA | Q04206 | 1/20 | 0.57 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.57 |
| ▸ | CNR1 | P21554 | 12/20 | 0.47 |
| ▸ | CNR2 | P34972 | 12/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10389086 | 0.95 | NPC1 (0.55) | NPC1RAB9AMAPK1SMN1; SMN2CASP3 | |
| SCHEMBL10387938 | 0.89 | NPC1 (0.69) | NPC1RAB9AMAPK1SMN1; SMN2CASP3 | |
| SCHEMBL10387261 | 0.85 | NPC1 (0.63) | NPC1RAB9AMAPK1SMN1; SMN2CASP3 | |
| SCHEMBL10389090 | 0.85 | NPC1 (0.56) | NPC1RAB9AMAPK1SMN1; SMN2CASP3 | |
| SCHEMBL13528805 | 0.85 | NPC1 (0.58) | NPC1RAB9AMAPK1SMN1; SMN2CASP3 | |
| SCHEMBL10388173 | 0.84 | NPC1 (0.65) | NPC1RAB9AMAPK1SMN1; SMN2CASP3 | |
| SCHEMBL10389123 | 0.83 | NPC1 (0.60) | NPC1RAB9AMAPK1SMN1; SMN2CASP3 | |
| SCHEMBL10387264 | 0.83 | NPC1 (0.60) | NPC1RAB9AMAPK1SMN1; SMN2CASP3 | |
| SCHEMBL10387894 | 0.83 | NPC1 (0.60) | NPC1RAB9AMAPK1SMN1; SMN2CASP3 | |
| SCHEMBL10387790 | 0.83 | NPC1 (0.60) | NPC1RAB9AMAPK1SMN1; SMN2CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4924015-A | PREPARING METALLIC COATINGS AND IMAGES | CIBA-GEIGY CORPORATION (US) | 1990-05-08 | — | — | US | disclosed |
| EP-0298034-A2 | Substituted anthraquinones and their use in epoxy resins | CIBA-GEIGY AG (CH) | 1989-01-04 | — | — | EP | disclosed |