Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.57 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.57 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10390960 | 0.91 | BRD4 (0.58) | BRD4LIN28AFYNSMN1; SMN2KDM4E | |
| SCHEMBL10390982 | 0.91 | BRD4 (0.70) | BRD4LIN28AFYNSMN1; SMN2KDM4E | |
| SCHEMBL10389904 | 0.89 | BRD4 (0.48) | BRD4LIN28AFYNSMN1; SMN2KDM4E | |
| SCHEMBL10389916 | 0.85 | BRD4 (0.78) | BRD4LIN28ASMN1; SMN2KDM4EMEN1 | |
| SCHEMBL10389969 | 0.84 | BRD4 (0.60) | BRD4LIN28AFYNSMN1; SMN2KDM4E | |
| SCHEMBL10389389 | 0.84 | BRD4 (0.54) | BRD4LIN28AFYNSMN1; SMN2KDM4E | |
| SCHEMBL10389951 | 0.80 | BRD4 (0.49) | BRD4LIN28AFYNSMN1; SMN2KDM4E | |
| SCHEMBL10768749 | 0.79 | MEN1 (0.55) | FYNSMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL10389630 | 0.79 | BRD4 (0.74) | BRD4LIN28AFYNSMN1; SMN2KDM4E | |
| SCHEMBL10769715 | 0.78 | FYN (0.61) | FYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4892873-A | MUSCLE RELAXANTS, ANTIEPILEPTIC, AN XIOLYTIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1990-01-09 | — | — | US | disclosed |
| US-4767765-A | ANXIOLYTIC OR ANTIEPILEPTIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1988-08-30 | — | — | US | disclosed |
| US-4654343-A | USEFUL AS ANXIOLYTIC OR ANTIEPILEPTIC AGENTS AS WELL AS SEDATIVE-HYPNOTIC AND SKELETAL MUSCLE RELAXANT AGENTS | AMERICAN CYANAMID COMPANY (US) | 1987-03-31 | — | — | US | disclosed |