Sugi Predict

Sugi Predict / Compounds / SCHEMBL103896

SCHEMBL103896

SCHEMBL103896

CCCCCCC(=O)NC

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HSP90AA1 P07900 1/20 0.67
▸ FAAH O00519 4/20 0.64
▸ MEN1 O00255 2/20 0.59
▸ KMT2A Q03164 2/20 0.59
▸ MAPK1 P28482 1/20 0.59
▸ CES2 O00748 3/20 0.56
▸ CES1 P23141 3/20 0.56
▸ GPR84 Q9NQS5 7/20 0.54
▸ PPARG P37231 6/20 0.54
▸ PPARD Q03181 6/20 0.54
▸ PPARA Q07869 6/20 0.54
▸ HDAC11 Q96DB2 5/20 0.54
▸ TSHR P16473 4/20 0.54
▸ ALDH1A1 P00352 2/20 0.54
▸ TLR2 O60603 2/20 0.54
▸ TDP1 Q9NUW8 2/20 0.54
▸ FABP4 P15090 2/20 0.54
▸ PTPN1 P18031 2/20 0.54
▸ SLC22A6 Q4U2R8 1/20 0.54
▸ SLC22A8 Q8TCC7 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6683800 1.00 HSP90AA1 (0.67) HSP90AA1FAAHMEN1KMT2AMAPK1
SCHEMBL6972741 1.00 HSP90AA1 (0.67) HSP90AA1FAAHMEN1KMT2AMAPK1
SCHEMBL76488 1.00 HSP90AA1 (0.67) HSP90AA1FAAHMEN1KMT2AMAPK1
SCHEMBL18673409 1.00 HSP90AA1 (0.67) HSP90AA1FAAHMEN1KMT2AMAPK1
SCHEMBL2248552 1.00 HSP90AA1 (0.67) HSP90AA1FAAHMEN1KMT2AMAPK1
SCHEMBL2485912 1.00 HSP90AA1 (0.67) HSP90AA1FAAHMEN1KMT2AMAPK1
SCHEMBL734547 1.00 HSP90AA1 (0.67) HSP90AA1FAAHMEN1KMT2AMAPK1
SCHEMBL18591622 1.00 HSP90AA1 (0.67) HSP90AA1FAAHMEN1KMT2AMAPK1
SCHEMBL1649096 1.00 HSP90AA1 (0.67) HSP90AA1FAAHMEN1KMT2AMAPK1
SCHEMBL2485142 1.00 HSP90AA1 (0.67) HSP90AA1FAAHMEN1KMT2AMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 193 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110357889-A Protein degradation target compound, its antitumor application thereof, wherein mesosome and intermediate application 上海科技大学 2019-10-22 — — CN claimed
CN-109912655-A Alk protein degradation agent and its antitumor application thereof 上海科技大学 2019-06-21 — — CN claimed
EP-2370486-A1 BRUSH COPOLYMERS Bausch & Lomb Incorporated (US) 2011-10-05 — — EP claimed
WO-2010078149-A1 BRUSH COPOLYMERS BAUSCH & LOMB INCORPORATED (US) 2010-07-08 — — WO claimed
WO-2026106260-A1 NOVEL DIPHENYLETHER DERIVATIVE AND USE THEREOF 광주과학기술원 2026-05-21 — — WO disclosed
US-20250064837-A1 TARGET PROTEIN DEGRADATION COMPOUNDS, THEIR ANTI-TUMOR USE, THEIR INTERMEDIATES AND USE OF INTERMEDIATES SHANGHAITECH UNIVERSITY (CN) 2025-02-27 — — US disclosed
US-12226424-B2 Target protein degradation compounds, their anti-tumor use, their intermediates and use of intermediates SHANGHAITECH UNIVERSITY (CN) 2025-02-18 — — US disclosed
WO-2024151465-A1 PROTEASE INHIBITORS FOR TREATING OR PREVENTING CORONAVIRUS INFECTION MERCK SHARP & DOHME LLC (US) 2024-07-18 — — WO disclosed
US-20240239934-A1 FUMARIC ACID DIESTER RESIN, FILM AND POLARIZING PLATE TOSOH CORPORATION (JP) 2024-07-18 — — US disclosed
US-20240239934-A1 FUMARIC ACID DIESTER RESIN, FILM AND POLARIZING PLATE TOSOH CORPORATION (JP) 2024-07-18 — — US disclosed
US-12036209-B2 Compounds and methods for the targeted degradation of Interleukin-1 receptor-associated kinase 4 polypeptides ARVINAS OPERATIONS, INC. (US) 2024-07-16 — — US disclosed
CN-117802594-A Production process of nylon 6 crimped yarn 福建省恒申合纤科技有限公司 2024-04-02 — — CN disclosed
EP-0997463-A1 NAPHTHYRIDINE DERIVATIVES OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) 2000-05-03 — — EP disclosed
US-5864043-A CARDIOVASCULAR DISORDERS AND ANGIOTENSIN ANTAGONIST KARL THOMAE GMBH (DE) 1999-01-26 — — US disclosed
US-5827863-A Pyrazole derivatives as angiotensin II antagonists J. URIACH & CIA, S.A. (ES) 1998-10-27 — — US disclosed
US-5541229-A ANGIOITENSIN II ANTAGONIST AS HYPOTENSIVE AGENTS, ANTIISCHEMIC AGENTS AND CARDIOVASCULAR DISORDERS DR. KARL THOMAE GMBH (DE) 1996-07-30 — — US disclosed
EP-0721454-A1 NEW PYRAZOLE DERIVATIVES AS ANGIOTENSIN II ANTAGONIST J. URIACH & CIA. S.A. (ES) 1996-07-17 — — EP disclosed
WO-1996004273-A1 NEW PYRAZOLE DERIVATIVES AS ANGIOTENSIN II ANTAGONIST J. URIACH & CIA, S.A. (ES) 1996-02-15 — — WO disclosed
US-5336732-A Dispersing polyphenylene ether in polyamide matrix ALLIEDSIGNAL INC. 1994-08-09 — — US disclosed
EP-0050790-A1 Preparation of alpha-chlorinated nitrogen heterocycles BAYER AG (DE) 1982-05-05 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12036209-B2 Compounds and methods for the targeted degradation of Interleukin-1 receptor-associated kinase 4 polypeptides IRAK1, IRAK4, IRAK2 HSP90AA1 1607/4885FAAH 3827/4885MEN1 2168/4885
US-20250064837-A1 TARGET PROTEIN DEGRADATION COMPOUNDS, THEIR ANTI-TUMOR USE, THEIR INTERMEDIATES AND USE OF INTERMEDIATES UFM1, SUMO1, SUMO2 HSP90AA1 1006/4885FAAH 3464/4885MEN1 4056/4885
US-12226424-B2 Target protein degradation compounds, their anti-tumor use, their intermediates and use of intermediates UFM1, SUMO1, SUMO2 HSP90AA1 933/4885FAAH 3561/4885MEN1 4125/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.