Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.57 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.57 |
| ▸ | FYN | P06241 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.43 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10391025 | 0.90 | BRD4 (0.51) | BRD4LIN28AFYNKDM4EGABRA1 | |
| SCHEMBL10389280 | 0.88 | BRD4 (0.74) | BRD4LIN28AKDM4EGABRA1GABRG2 | |
| SCHEMBL10389391 | 0.85 | BRD4 (0.77) | BRD4LIN28AFYNKDM4EGABRA1 | |
| SCHEMBL10391028 | 0.85 | BRD4 (0.55) | BRD4LIN28AFYNKDM4EGABRA1 | |
| SCHEMBL10389389 | 0.84 | BRD4 (0.54) | BRD4LIN28AFYNKDM4EGABRA1 | |
| SCHEMBL10389969 | 0.83 | BRD4 (0.60) | BRD4LIN28AFYNKDM4EGABRA1 | |
| SCHEMBL10389394 | 0.80 | POLB (0.52) | BRD4LIN28AKDM4EMAPK1SMN1; SMN2 | |
| SCHEMBL10390956 | 0.80 | BRD4 (0.71) | BRD4LIN28AKDM4EGABRA1GABRG2 | |
| SCHEMBL10389974 | 0.79 | BRD4 (0.67) | BRD4LIN28AKDM4EGABRA1GABRG2 | |
| SCHEMBL10389956 | 0.78 | BRD4 (0.66) | BRD4LIN28AKDM4EGABRA1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4892873-A | MUSCLE RELAXANTS, ANTIEPILEPTIC, AN XIOLYTIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1990-01-09 | — | — | US | disclosed |
| US-4767765-A | ANXIOLYTIC OR ANTIEPILEPTIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1988-08-30 | — | — | US | disclosed |
| US-4654343-A | USEFUL AS ANXIOLYTIC OR ANTIEPILEPTIC AGENTS AS WELL AS SEDATIVE-HYPNOTIC AND SKELETAL MUSCLE RELAXANT AGENTS | AMERICAN CYANAMID COMPANY (US) | 1987-03-31 | — | — | US | disclosed |