Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 7/20 | 0.42 |
| ▸ | NOS1 | P29475 | 5/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | PNP | P00491 | 2/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | PAH | P00439 | 1/20 | 0.31 |
| ▸ | PDE5A | O76074 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9308669 | 0.87 | HPRT1 (0.41) | HPRT1NOS1TLR7PNPNOS3 | |
| SCHEMBL9309722 | 0.87 | HPRT1 (0.41) | HPRT1NOS1TLR7PNPNOS3 | |
| SCHEMBL9021973 | 0.84 | HPRT1 (0.43) | HPRT1NOS1PNPNOS3NOS2 | |
| SCHEMBL3436892 | 0.81 | HPRT1 (0.43) | HPRT1NOS1TLR7PNPNOS3 | |
| SCHEMBL10395198 | 0.81 | HPRT1 (0.43) | HPRT1NOS1TLR7PNPNOS3 | |
| SCHEMBL8080082 | 0.81 | HPRT1 (0.45) | HPRT1NOS1TLR7PNPNOS3 | |
| SCHEMBL9021971 | 0.80 | HPRT1 (0.40) | HPRT1NOS1NOS3NOS2USP2 | |
| SCHEMBL9310753 | 0.79 | HPRT1 (0.46) | HPRT1NOS1NOS3NOS2USP2 | |
| SCHEMBL8353453 | 0.78 | HPRT1 (0.45) | HPRT1NOS1NOS3NOS2USP2 | |
| SCHEMBL5430798 | 0.76 | HPRT1 (0.42) | HPRT1NOS1TLR7PNPNOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4968674-A | Antiviral carbocyclic purine nucleosides | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-11-06 | — | — | US | claimed |
| EP-0236935-A2 | Carboxylic purine nucleosides, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1987-09-16 | — | — | EP | claimed |
| US-4968674-A | Antiviral carbocyclic purine nucleosides | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-11-06 | — | — | US | disclosed |
| EP-0236935-A2 | Carboxylic purine nucleosides, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1987-09-16 | — | — | EP | disclosed |