Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.54 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.48 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 2/20 | 0.44 |
| ▸ | RXRB | P28702 | 2/20 | 0.44 |
| ▸ | RXRG | P48443 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10395974 | 0.91 | TP53 (0.54) | MRGPRX4ALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL10396448 | 0.85 | NR4A2 (0.66) | MRGPRX4MCL1NR4A2NPC1RAB9A | |
| Benzene SCHEMBL28056879 | 0.80 | MAOB (0.64) | MRGPRX4MCL1NR4A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL1022035 | 0.80 | MAOB (0.64) | MRGPRX4MCL1NR4A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL10397859 | 0.78 | NR4A2 (0.69) | MRGPRX4NR4A2ALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9440598 | 0.78 | MAOB (0.62) | MRGPRX4MCL1NR4A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL30412532 | 0.77 | NR4A2 (0.74) | MRGPRX4NR4A2NPC1RAB9ANR1H4 | |
| SCHEMBL978508 | 0.77 | NR4A2 (0.74) | MRGPRX4NR4A2NPC1RAB9ANR1H4 | |
| SCHEMBL10397866 | 0.76 | POLB (0.53) | MRGPRX4MCL1NR4A2RAB9AALDH1A1 | |
| SCHEMBL686832 | 0.76 | KDM4E (0.57) | MCL1NPC1RAB9AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4910206-A | Endotoxin induced lung injury | SANDOZ PHARMACEUTICALS CORP. (US) | 1990-03-20 | — | — | US | disclosed |