SCHEMBL10397302

SCHEMBL10397302

CC(C)CCOC(=O)c1ccc(O)c(S(=O)(=O)c2cc(C(=O)OCCC(C)C)ccc2O)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 2/20 0.51
KDM4E B2RXH2 2/20 0.51
ALDH1A1 P00352 2/20 0.51
GAA P10253 1/20 0.51
KMT2A Q03164 1/20 0.51
MAPK1 P28482 2/20 0.50
HSD17B10 Q99714 1/20 0.50
POLB P06746 1/20 0.45
HDAC6 Q9UBN7 1/20 0.45
CA12 O43570 2/20 0.44
CA1 P00915 2/20 0.44
CA2 P00918 2/20 0.44
CA7 P43166 2/20 0.44
CA9 Q16790 2/20 0.44
CA14 Q9ULX7 2/20 0.44
ESR1 P03372 3/20 0.44
PTPN1 P18031 1/20 0.41
HSD17B2 P37059 1/20 0.40
STS P08842 1/20 0.39
CHRM1 P11229 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10397282 0.86 PTPN1 (0.50) KDM4EALDH1A1POLBHDAC6CA12
SCHEMBL10605834 0.84 KDM4E (0.62) KDM4EALDH1A1MAPK1POLBHDAC6
Water SCHEMBL10398700 0.83 KDM4E (0.61) KDM4EALDH1A1MAPK1POLBHDAC6
SCHEMBL10398684 0.82 ESR1 (0.66) KDM4EMAPK1POLBHDAC6ESR1
SCHEMBL10606130 0.81 CA1 (0.68) KDM4EALDH1A1GAAKMT2APOLB
SCHEMBL10398665 0.81 ESR1 (0.60) ALDH1A1MAPK1HDAC6ESR1STS
Water SCHEMBL10398682 0.80 CA1 (0.66) KDM4EALDH1A1GAAKMT2APOLB
SCHEMBL10398693 0.80 ESR1 (0.59) ALDH1A1MAPK1HDAC6ESR1STS
SCHEMBL10397263 0.80 ESR1 (0.59) ALDH1A1MAPK1HDAC6ESR1STS
SCHEMBL10398472 0.80 ESR1 (0.59) ALDH1A1MAPK1HDAC6ESR1STS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4965395-A BACTERICIDES YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 1990-10-23 US disclosed
EP-0224592-B1 P-HYDROXYBENZOIC ACID DERIVATIVES Yoshitomi Pharmaceutical Industries, Ltd. (JP) 1989-11-15 EP disclosed
EP-0224592-A1 p-HYDROXYBENZOIC ACID DERIVATIVES Yoshitomi Pharmaceutical Industries, Ltd. (JP) 1987-06-10 EP disclosed