Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1035521 | 1.00 | MEN1 (0.42) | MEN1KMT2ATSHRALDH1A1THRB | |
| SCHEMBL1034843 | 1.00 | MEN1 (0.42) | MEN1KMT2ATSHRALDH1A1THRB | |
| SCHEMBL9064397 | 0.88 | TSHR (0.41) | TSHRALDH1A1THRBCHRM5CHRM1 | |
| SCHEMBL20994131 | 0.86 | MEN1 (0.44) | MEN1KMT2ATSHRALDH1A1THRB | |
| SCHEMBL20994135 | 0.86 | MEN1 (0.44) | MEN1KMT2ATSHRALDH1A1THRB | |
| SCHEMBL20994134 | 0.86 | MEN1 (0.44) | MEN1KMT2ATSHRALDH1A1THRB | |
| SCHEMBL2809299 | 0.86 | MEN1 (0.44) | MEN1KMT2ATSHRALDH1A1THRB | |
| SCHEMBL21081977 | 0.86 | MEN1 (0.44) | MEN1KMT2ATSHRALDH1A1THRB | |
| SCHEMBL20994136 | 0.86 | MEN1 (0.44) | MEN1KMT2ATSHRALDH1A1THRB | |
| SCHEMBL21081954 | 0.86 | MEN1 (0.44) | MEN1KMT2ATSHRALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2029630-B1 | LOW STRESS DENTAL COMPOSITE CONTAINING PHOTOPOLYMERIZABLE AND PHOTOCLEAVABLE RESIN | DENTSPLY INT INC (US) | 2011-01-26 | — | — | EP | claimed |