Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 6/20 | 0.74 |
| ▸ | RARB | P10826 | 3/20 | 0.63 |
| ▸ | PLK1 | P53350 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | PLA2G4B | P0C869 | 5/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9407174 | 1.00 | PTPN11 (0.74) | PTPN11RARBPLK1TP53TSHR | |
| SCHEMBL10800801 | 1.00 | PTPN11 (0.74) | PTPN11RARBPLK1TP53TSHR | |
| SCHEMBL9723854 | 1.00 | PTPN11 (0.74) | PTPN11RARBPLK1TP53TSHR | |
| SCHEMBL8081703 | 1.00 | PTPN11 (0.74) | PTPN11RARBPLK1TP53TSHR | |
| SCHEMBL17835424 | 1.00 | PTPN11 (0.74) | PTPN11RARBPLK1TP53TSHR | |
| SCHEMBL6265322 | 1.00 | PTPN11 (0.74) | PTPN11RARBPLK1TP53TSHR | |
| SCHEMBL6691500 | 0.99 | PTPN11 (0.72) | PTPN11RARBPLK1TP53TSHR | |
| SCHEMBL6913917 | 0.97 | PTPN11 (0.70) | PTPN11RARBPLK1TP53TSHR | |
| SCHEMBL9187046 | 0.88 | PTPN11 (0.57) | PTPN11RARBPLK1TP53TSHR | |
| SCHEMBL9453349 | 0.88 | MEN1 (0.62) | PTPN11RARBPLK1TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4943386-A | FERROELECTRIC, GOOD RESPONSE AND MEMORY | DAINIPPON INK & CHEMICALS, INC. (JP) | 1990-07-24 | — | — | US | disclosed |