SCHEMBL10399103

SCHEMBL10399103

COc1ccccc1/C(=C/C=C/C(=O)NCCCCc1cccnc1)c1ccccc1

nearest known ligand 0.90

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PTAFR P25105 20/20 0.90

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10399106 1.00 PTAFR (0.90) PTAFR
SCHEMBL9520653 0.94 PTAFR (1.00) PTAFR
SCHEMBL9520641 0.94 PTAFR (1.00) PTAFR
SCHEMBL9519892 0.94 PTAFR (0.85) PTAFR
SCHEMBL9521726 0.94 PTAFR (0.85) PTAFR
SCHEMBL9519898 0.94 PTAFR (0.85) PTAFR
SCHEMBL10399206 0.91 PTAFR (0.80) PTAFR
SCHEMBL10399204 0.91 PTAFR (0.80) PTAFR
SCHEMBL9520861 0.88 PTAFR (1.00) PTAFR
SCHEMBL9520848 0.88 PTAFR (1.00) PTAFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4975438-A ANTICOAGULANT HOFFMANN-LA ROCHE INC. (US) 1990-12-04 US disclosed
US-4788206-A CARDIOVASCULAR DISORDERS, PLATELETS HOFFMANN-LA ROCHE INC. (US) 1988-11-29 US disclosed