Butylate

Butylate

SCHEMBL10399541

CCSC(=O)N(CC(C)C)CC(C)C.CCSC(=O)N(CC(C)C)CC(C)C.CCSC(=O)N(CC(C)C)CC(C)C

nearest known ligand 0.56

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Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.56
MAPK1 P28482 1/20 0.56
CA1 P00915 5/20 0.46
CA12 O43570 3/20 0.46
CA2 P00918 3/20 0.46
CA9 Q16790 3/20 0.46
ALDH1A1 P00352 2/20 0.37
MLYCD O95822 2/20 0.33
CHRNB2 P17787 1/20 0.31
CHRNB4 P30926 1/20 0.31
CHRNA3 P32297 1/20 0.31
CHRNA4 P43681 1/20 0.31
FPR1 P21462 1/20 0.31
HSD17B10 Q99714 1/20 0.31
KDM4E B2RXH2 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butylate SCHEMBL8539930 1.00 TSHR (0.56) TSHRMAPK1CA1CA12CA2
Butylate SCHEMBL66484 1.00 TSHR (0.56) TSHRMAPK1CA1CA12CA2
Butylate SCHEMBL787504 0.98 TSHR (0.54) TSHRMAPK1CA1CA12CA2
Butylate SCHEMBL11689530 0.98 TSHR (0.54) TSHRMAPK1CA1CA12CA2
Butylate SCHEMBL11576804 0.98 TSHR (0.54) TSHRMAPK1CA1CA12CA2
Butylate SCHEMBL10487951 0.98 TSHR (0.59) TSHRMAPK1CA1CA12CA2
Butylate SCHEMBL10487947 0.98 TSHR (0.54) TSHRMAPK1CA1CA12CA2
Butylate SCHEMBL10626195 0.98 TSHR (0.54) TSHRMAPK1CA1CA12CA2
Butylate SCHEMBL7778213 0.98 TSHR (0.54) TSHRMAPK1CA1CA12CA2
Butylate SCHEMBL395574 0.98 TSHR (0.54) TSHRMAPK1CA1CA12CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4911952-A Heating amylase, water mixture THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 1990-03-27 US disclosed