Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.71 |
| ▸ | AHR | P35869 | 4/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 2/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.35 |
| ▸ | PNMT | P11086 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | CASR | P41180 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11867927 | 0.91 | TSHR (0.60) | TSHRAHRTP53HSD17B10CYP3A4 | |
| SCHEMBL11866111 | 0.89 | TSHR (0.58) | TSHRAHRTP53HSD17B10CYP3A4 | |
| SCHEMBL11861140 | 0.87 | TSHR (0.56) | TSHRAHRTP53HSD17B10CYP3A4 | |
| SCHEMBL5384985 | 0.86 | TSHR (0.75) | TSHRAHRTP53HSD17B10CYP3A4 | |
| SCHEMBL11865760 | 0.85 | TSHR (0.54) | TSHRAHRTP53CYP3A4KIF11 | |
| SCHEMBL1843312 | 0.83 | TSHR (1.00) | TSHRAHRTP53HSD17B10CYP3A4 | |
| SCHEMBL11862196 | 0.82 | TSHR (0.50) | TSHRAHRTP53ALDH1A1RAD51 | |
| SCHEMBL11863809 | 0.82 | TSHR (0.50) | TSHRAHRTP53HSD17B10CYP3A4 | |
| SCHEMBL11871111 | 0.82 | TSHR (0.50) | TSHRAHRTP53KIF11CYP19A1 | |
| SCHEMBL11591961 | 0.81 | TSHR (0.68) | TSHRAHRTP53HSD17B10CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4978798-A | Method of making halobenzophenones and intermediates thereof | OCCIDENTAL CHEMICAL CORPORATION (US) | 1990-12-18 | — | — | US | claimed |
| US-4978798-A | Method of making halobenzophenones and intermediates thereof | OCCIDENTAL CHEMICAL CORPORATION (US) | 1990-12-18 | — | — | US | disclosed |