Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 4/20 | 0.62 |
| ▸ | CYP4A11 | Q02928 | 4/20 | 0.62 |
| ▸ | PPARA | Q07869 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10982252 | 0.93 | CYP4F2 (0.50) | CYP4F2CYP4A11PPARATDP1HRH3 | |
| SCHEMBL10973564 | 0.90 | PPARA (0.53) | CYP4F2CYP4A11PPARATDP1CA2 | |
| SCHEMBL13250321 | 0.86 | CYP4F2 (0.49) | CYP4F2CYP4A11TDP1HRH3F2RL1 | |
| SCHEMBL1587126 | 0.86 | MEN1 (0.45) | CYP4F2CYP4A11TDP1CA2TSHR | |
| SCHEMBL7420345 | 0.86 | CYP4F2 (0.49) | CYP4F2CYP4A11TDP1 | |
| SCHEMBL20025191 | 0.85 | CYP4A11 (0.46) | CYP4F2CYP4A11PPARATDP1CA2 | |
| SCHEMBL18761383 | 0.84 | PPARA (0.50) | CYP4F2CYP4A11PPARAHRH3 | |
| SCHEMBL15608606 | 0.84 | CYP4F2 (0.44) | CYP4F2CYP4A11TDP1CA2HRH3 | |
| SCHEMBL7420342 | 0.84 | CYP4F2 (0.44) | CYP4F2CYP4A11TDP1CA2HRH3 | |
| SCHEMBL18761597 | 0.84 | CYP4F2 (0.44) | CYP4F2CYP4A11TDP1HRH3F2RL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107849008-B | Octahydrocyclopenta [ c ] pyrrole derivative, preparation method and medical application thereof | 四川海思科制药有限公司 | 2021-04-09 | — | — | CN | disclosed |
| US-4977144-A | ADENOSINE AGONISTS | CIBA-GEIGY CORPORATION (US) | 1990-12-11 | — | — | US | disclosed |
| EP-0354180-A2 | Certain imidazo[4,5-b]pyridine derivatives | CIBA-GEIGY AG (CH) | 1990-02-07 | — | — | EP | disclosed |