Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | FDPS | P14324 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14560518 | 0.87 | TDP1 (0.76) | TDP1GAARECQLALDH1A1CYP1A2 | |
| SCHEMBL1537376 | 0.85 | TDP1 (0.69) | TDP1GAARECQLALDH1A1CYP1A2 | |
| SCHEMBL9282228 | 0.84 | TDP1 (0.67) | TDP1GAARECQLALDH1A1CYP1A2 | |
| SCHEMBL30538659 | 0.84 | TDP1 (0.67) | TDP1GAARECQLALDH1A1CYP1A2 | |
| SCHEMBL26346465 | 0.84 | TDP1 (0.67) | TDP1GAARECQLALDH1A1CYP1A2 | |
| SCHEMBL15377348 | 0.84 | TDP1 (0.67) | TDP1GAARECQLALDH1A1CYP1A2 | |
| SCHEMBL3084331 | 0.84 | TDP1 (0.67) | TDP1GAARECQLALDH1A1CYP1A2 | |
| SCHEMBL15027451 | 0.84 | TDP1 (0.67) | TDP1GAARECQLALDH1A1CYP1A2 | |
| SCHEMBL31578910 | 0.84 | TDP1 (0.67) | TDP1GAARECQLALDH1A1CYP1A2 | |
| SCHEMBL4308548 | 0.84 | TDP1 (0.67) | TDP1GAARECQLALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4952689-A | 3-(substituted propylidene)-2-azetidinone derivates for blood platelet aggregation | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1990-08-28 | — | — | US | disclosed |
| EP-0365364-A2 | 2-Azetidinone derivatives | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1990-04-25 | — | — | EP | disclosed |