SCHEMBL10400548

SCHEMBL10400548

O=C(O)C1CN1.[LiH]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27733793 1.00
SCHEMBL9232183 0.97
SCHEMBL242266 0.97
SCHEMBL5388393 0.97
SCHEMBL10399513 0.93
Ammonia Solution, Strong SCHEMBL10942345 0.93
SCHEMBL10517356 0.93 CYP1A2 (0.59)
SCHEMBL10517369 0.93 CYP1A2 (0.59)
SCHEMBL2810164 0.93 CYP1A2 (0.59)
Ammonia Solution, Strong SCHEMBL10948146 0.93 CYP1A2 (0.59)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0078853-B1 PROCESS FOR PREPARING BETA-CHLOROALANINE MITSUI TOATSU CHEMICALS, Inc. (JP) 1985-11-13 EP claimed
US-4484003-A Preparation process of β-chloroalanine MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1984-11-20 US claimed
EP-0078853-A1 PROCESS FOR PREPARING BETA-CHLOROALANINE MITSUI TOATSU CHEMICALS, Inc. (JP) 1983-05-18 EP claimed
CN-117715658-A Method for inhibiting RAS 锐新医药公司 2024-03-15 CN disclosed
CN-116722143-B Application of lithium carboxylate with N-containing six-membered ring structure and anode of anode-free lithium metal battery 哈尔滨工业大学 2024-03-01 CN disclosed
CN-117616031-A RAS inhibitors for the treatment of cancer 锐新医药公司 2024-02-27 CN disclosed
CN-116722143-A Application of lithium carboxylate with N-containing six-membered ring structure and anode of anode-free lithium metal battery 哈尔滨工业大学 2023-09-08 CN disclosed
CN-114980976-A Covalent RAS inhibitors and uses thereof 锐新医药公司 2022-08-30 CN disclosed
US-4935527-A SEPARATION FROM IMPURITIES BY ION EXCHANGING ON A CATIONIC EXCHANGER BED RESEARCH ASSOCIATION FOR UTILIZATION OF LIGHT OIL (JP) 1990-06-19 US disclosed
EP-0191462-A1 Purification of aziridine-2-carboxylic acid salts RESEARCH ASSOCIATION FOR UTILIZATION OF LIGHT OIL (JP) 1986-08-20 EP disclosed
EP-0079390-B1 PROCESS FOR PREPARING BETA-HYDROXY AMINO ACID MITSUI TOATSU CHEMICALS, Inc. (JP) 1985-12-27 EP disclosed
EP-0030475-B1 PROCESS FOR PRODUCING SOLUTIONS OF AZIRIDINE-2-CARBOXYLIC ACID SALTS MITSUI TOATSU CHEMICALS, Inc. (JP) 1984-03-14 EP disclosed
US-4393000-A DEHYDROHALOGENATION OF ALPHA-HALO-BETA-AMINOPROPIONITRILE MITSUI TOATSU CHEMICALS, INC. (JP) 1983-07-12 US disclosed
EP-0079390-A1 PROCESS FOR PREPARING BETA-HYDROXY AMINO ACID MITSUI TOATSU CHEMICALS, Inc. (JP) 1983-05-25 EP disclosed
EP-0078853-A1 PROCESS FOR PREPARING BETA-CHLOROALANINE MITSUI TOATSU CHEMICALS, Inc. (JP) 1983-05-18 EP disclosed
EP-0030474-B1 PROCESS FOR THE PRODUCTION OF DL-SERINES MITSUI TOATSU CHEMICALS, Inc. (JP) 1983-01-19 EP disclosed
US-4304933-A HEATING AZIRIDINE-2-CARBOXYLIC ACID ON ION EXCHANGE RESIN MITSUI TOATSU CHEMICALS, INC. (JP) 1981-12-08 US disclosed
EP-0030870-A1 Process for producing solutions of aziridine-2-carboxylic acid salt MITSUI TOATSU CHEMICALS, Inc. (JP) 1981-06-24 EP disclosed
EP-0030474-A1 Process for the production of DL-serines MITSUI TOATSU CHEMICALS, Inc. (JP) 1981-06-17 EP disclosed
EP-0030475-A1 Process for producing solutions of aziridine-2-carboxylic acid salts MITSUI TOATSU CHEMICALS, Inc. (JP) 1981-06-17 EP disclosed