Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ESRRB | O95718 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1660809 | 1.00 | AKT1 (0.40) | AKT1KCNA5TBXAS1KMT2AESRRB | |
| SCHEMBL1660808 | 1.00 | AKT1 (0.40) | AKT1KCNA5TBXAS1KMT2AESRRB | |
| SCHEMBL1040067 | 1.00 | AKT1 (0.40) | AKT1KCNA5TBXAS1KMT2AESRRB | |
| SCHEMBL9421149 | 0.85 | HMGCR (0.39) | — | |
| SCHEMBL6320596 | 0.85 | HMGCR (0.39) | — | |
| SCHEMBL6900099 | 0.85 | HMGCR (0.39) | — | |
| SCHEMBL6900093 | 0.85 | HMGCR (0.39) | — | |
| SCHEMBL9420672 | 0.79 | CNR2 (0.40) | — | |
| SCHEMBL9420668 | 0.79 | CNR2 (0.40) | — | |
| SCHEMBL9735655 | 0.76 | KMT2A (0.40) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9259872-B2 | Multiparticulates | EURO-CELTIQUE S.A. (LU) | 2016-02-16 | — | — | US | claimed |
| US-9259872-B2 | Multiparticulates | EURO-CELTIQUE S.A. (LU) | 2016-02-16 | — | — | US | disclosed |
| CN-103462904-A | Multiparticulates of preferably an opioid, and method of manufacturing using extrusion | EURO CELTIQUE SA | 2013-12-25 | — | — | CN | disclosed |
| EP-2269582-A2 | Multiparticulates of preferably an opioid, and method of manufacturing using extrusion | EURO-CELTIQUE S.A. (LU) | 2011-01-05 | — | — | EP | disclosed |
| US-20080260815-A1 | Extruded with water permeability modifier and platicizer that also acts as lubricant; pH independent release profile; opioid controlled release | EURO-CELTIQUE S.A. (LU) | 2008-10-23 | — | — | US | disclosed |
| CN-101052379-A | Multiparticulates of preferably opioids and manufacturing process using extrusion | EURO CELTIQUE SA (LU) | 2007-10-10 | — | — | CN | disclosed |
| EP-1809249-A2 | MULTIPARTICULATES OF PREFERABLY AN OPIOID, AND METHOD OF MANUFACTURING USING EXTRUSION | Euroceltique S.A. (LU) | 2007-07-25 | — | — | EP | disclosed |
| WO-2006024881-A2 | MULTIPARTICULATES OF PREFERABLY AN OPIOID, AND METHOD OF MANUFACTURING USING EXTRUSION | EURO-CELTIQUE S.A. (LU) | 2006-03-09 | — | — | WO | disclosed |