Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.75 |
| ▸ | APAF1 | O14727 | 2/20 | 0.75 |
| ▸ | LMNA | P02545 | 1/20 | 0.75 |
| ▸ | TSHR | P16473 | 1/20 | 0.75 |
| ▸ | APEX1 | P27695 | 1/20 | 0.75 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.75 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.75 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.75 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.75 |
| ▸ | MAPT | P10636 | 3/20 | 0.74 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.74 |
| ▸ | MMP2 | P08253 | 1/20 | 0.74 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.74 |
| ▸ | CNR1 | P21554 | 1/20 | 0.74 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.74 |
| ▸ | NR1I2 | O75469 | 6/20 | 0.58 |
| ▸ | HTR2C | P28335 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | PPARG | P37231 | 2/20 | 0.56 |
| ▸ | ALB | P02768 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4627396 | 1.00 | TDP1 (0.75) | TDP1APAF1LMNATSHRAPEX1 | |
| SCHEMBL14600780 | 1.00 | TDP1 (0.75) | TDP1APAF1LMNATSHRAPEX1 | |
| SCHEMBL4124254 | 1.00 | TDP1 (0.75) | TDP1APAF1LMNATSHRAPEX1 | |
| SCHEMBL4124260 | 1.00 | TDP1 (0.75) | TDP1APAF1LMNATSHRAPEX1 | |
| SCHEMBL4627402 | 1.00 | TDP1 (0.75) | TDP1APAF1LMNATSHRAPEX1 | |
| SCHEMBL4141299 | 1.00 | TDP1 (0.75) | TDP1APAF1LMNATSHRAPEX1 | |
| SCHEMBL4141307 | 1.00 | TDP1 (0.75) | TDP1APAF1LMNATSHRAPEX1 | |
| SCHEMBL5494777 | 1.00 | TDP1 (0.75) | TDP1APAF1LMNATSHRAPEX1 | |
| SCHEMBL3299039 | 0.94 | TDP1 (0.67) | TDP1APAF1LMNATSHRAPEX1 | |
| SCHEMBL4132476 | 0.94 | TDP1 (0.67) | TDP1APAF1LMNATSHRAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4935508-A | Acylation of 7-aminocephalosporin with alkyl 2-(2-amino-thiazol-4-yl)-2-oximinoacetate | BRISTOL-MYERS COMPANY (US) | 1990-06-19 | — | — | US | disclosed |