Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KLK7 | P49862 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28293338 | 0.77 | PTGER1 (0.43) | PTGER1ESR1HPGDPOLBALDH1A1 | |
| SCHEMBL1038228 | 0.74 | HCRTR2 (0.65) | PTGER1ESR1HCRTR2L3MBTL1ALDH1A1 | |
| SCHEMBL1039606 | 0.73 | TSHR (0.56) | PTGER1ESR1HPGDTSHRALDH1A1 | |
| SCHEMBL8337800 | 0.71 | PTGER1 (0.62) | PTGER1HPGDMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL12956317 | 0.68 | TEAD1 (0.58) | PTGER1ESR1HCRTR2POLBALDH1A1 | |
| SCHEMBL1040792 | 0.68 | TEAD1 (0.58) | PTGER1HCRTR2TSHRALDH1A1MEN1 | |
| SCHEMBL27887722 | 0.64 | HCRTR2 (0.43) | ESR1HCRTR2POLBL3MBTL1ALDH1A1 | |
| SCHEMBL24109992 | 0.64 | PTGER1 (0.39) | PTGER1HCRTR2TSHRALDH1A1MEN1 | |
| SCHEMBL4286533 | 0.63 | ESR1 (0.48) | ESR1POLBTSHRALDH1A1MEN1 | |
| SCHEMBL14676795 | 0.63 | HCRTR2 (0.44) | PTGER1ESR1HCRTR2POLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1554239-B1 | SULFONYLAMINO-ACETIC ACID DERIVATIVES AND THEIR USE AS OREXIN RECEPTOR ANTAGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2011-01-26 | — | — | EP | claimed |