⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8159426 | 0.76 | — | — | |
| SCHEMBL10402964 | 0.75 | — | — | |
| SCHEMBL1613114 | 0.73 | MPI (0.31) | — | |
| SCHEMBL6826865 | 0.72 | — | — | |
| SCHEMBL12216606 | 0.72 | — | — | |
| SCHEMBL10402005 | 0.71 | — | — | |
| SCHEMBL11277667 | 0.70 | — | — | |
| SCHEMBL10403284 | 0.70 | — | — | |
| SCHEMBL8007391 | 0.70 | — | — | |
| SCHEMBL7537680 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100261167-A1 | In vivo screen using chemical inducers of dimerization | THE TRUSTREES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2010-10-14 | — | — | US | disclosed |
| US-20100261167-A1 | In vivo screen using chemical inducers of dimerization | THE TRUSTREES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2010-10-14 | — | — | US | disclosed |
| US-7419780-B2 | Methods and assays for screening protein targets | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2008-09-02 | — | — | US | disclosed |
| US-7419780-B2 | Methods and assays for screening protein targets | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2008-09-02 | — | — | US | disclosed |
| US-4914206-A | ANTIBIOTICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-04-03 | — | — | US | disclosed |
| EP-0226896-A2 | Lankacidin derivatives and production thereof | Takeda Chemical Industries, Ltd. (JP) | 1987-07-01 | — | — | EP | disclosed |