Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRA | P18433 | 1/20 | 0.54 |
| ▸ | FDPS | P14324 | 1/20 | 0.50 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.47 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.47 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.47 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.47 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31450615 | 0.81 | PTPRA (0.54) | PTPRAFDPSGRIN2DGRIN3BGRIN1 | |
| SCHEMBL28714934 | 0.81 | PTPRA (0.54) | PTPRAFDPSGRIN2DGRIN3BGRIN1 | |
| SCHEMBL198454 | 0.81 | PTPRA (0.54) | PTPRAFDPSGRIN2DGRIN3BGRIN1 | |
| SCHEMBL6921059 | 0.78 | PTPRA (0.63) | PTPRAFDPSGRIN2DGRIN3BGRIN1 | |
| SCHEMBL10403587 | 0.78 | GRIN2D (0.56) | PTPRAFDPSGRIN2DGRIN3BGRIN1 | |
| SCHEMBL10403994 | 0.75 | GRIN2D (0.45) | PTPRAFDPSGRIN2DGRIN3BGRIN1 | |
| SCHEMBL5762419 | 0.75 | PTPRA (0.59) | PTPRAFDPSGRIN2DGRIN3BGRIN1 | |
| SCHEMBL4028421 | 0.75 | GRIN2D (0.61) | PTPRAFDPSGRIN2DGRIN3BGRIN1 | |
| SCHEMBL7085644 | 0.75 | PTPRA (0.59) | PTPRAFDPSGRIN2DGRIN3BGRIN1 | |
| SCHEMBL7979864 | 0.75 | PTPRA (0.59) | PTPRAFDPSGRIN2DGRIN3BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4914206-A | ANTIBIOTICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-04-03 | — | — | US | disclosed |
| EP-0226896-A2 | Lankacidin derivatives and production thereof | Takeda Chemical Industries, Ltd. (JP) | 1987-07-01 | — | — | EP | disclosed |