Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 4/20 | 0.56 |
| ▸ | HTR2A | P28223 | 4/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 2/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.44 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3290730 | 0.82 | HRH1 (0.68) | HRH1HTR2ATAAR1ADRA2ALMNA | |
| SCHEMBL10537483 | 0.80 | HRH1 (0.54) | HRH1HTR2ATAAR1ADRA2ALMNA | |
| SCHEMBL8217290 | 0.80 | HRH1 (0.61) | HRH1HTR2ATAAR1ADRA2ADPP4 | |
| SCHEMBL27321444 | 0.79 | HRH1 (0.65) | HRH1HTR2ATAAR1ADRA2ALMNA | |
| SCHEMBL844862 | 0.79 | HRH1 (0.65) | HRH1HTR2ATAAR1ADRA2ALMNA | |
| SCHEMBL2732016 | 0.79 | HRH1 (0.65) | HRH1HTR2ATAAR1ADRA2ALMNA | |
| SCHEMBL21141876 | 0.78 | GRM2 (0.52) | HRH1HTR2ATAAR1ADRA2AADRA2C | |
| SCHEMBL7963200 | 0.76 | HRH1 (0.50) | HRH1HTR2ATAAR1ADRA2ALMNA | |
| SCHEMBL27587669 | 0.76 | HRH1 (0.50) | HRH1HTR2AADRA2AADRA2CLMNA | |
| SCHEMBL8020117 | 0.76 | SCN4A (0.42) | HRH1HTR2AADRA2AADRA2CLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4931470-A | Antiarrhythmic method | ELI LILLY AND COMPANY (US) | 1990-06-05 | — | — | US | disclosed |
| US-4197313-A | USE OF 9-AMINOALKYL-9-(HYDROXY, CYANO OR CARBAMOYL)-FLUORENES | ELI LILLY AND COMPANY (US) | 1980-04-08 | — | — | US | disclosed |