Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.33 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10401935 | 0.83 | POLB (0.44) | POLBKMT2ASMN1; SMN2HSD17B10TSHR | |
| SCHEMBL10401934 | 0.77 | POLB (0.52) | POLBKMT2ASMN1; SMN2HSD17B10TSHR | |
| SCHEMBL10403874 | 0.77 | POLB (0.44) | POLBKMT2ASMN1; SMN2HSD17B10TSHR | |
| SCHEMBL19369802 | 0.74 | POLB (0.53) | POLBKMT2ASMN1; SMN2HSD17B10TSHR | |
| SCHEMBL10403035 | 0.74 | KMT2A (0.37) | KMT2AALDH1A1 | |
| SCHEMBL10403137 | 0.74 | KMT2A (0.37) | KMT2A | |
| SCHEMBL10401915 | 0.73 | GAA (0.50) | POLBKMT2ASMN1; SMN2ALDH1A1GAA | |
| SCHEMBL10401989 | 0.72 | TSHR (0.44) | POLBKMT2ASMN1; SMN2HSD17B10TSHR | |
| SCHEMBL19361775 | 0.70 | POLB (0.48) | POLBKMT2ASMN1; SMN2HSD17B10TSHR | |
| SCHEMBL10402744 | 0.70 | HSD17B10 (0.43) | POLBKMT2ASMN1; SMN2HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4914206-A | ANTIBIOTICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-04-03 | — | — | US | disclosed |
| EP-0226896-A2 | Lankacidin derivatives and production thereof | Takeda Chemical Industries, Ltd. (JP) | 1987-07-01 | — | — | EP | disclosed |