Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 2/20 | 0.42 |
| ▸ | GPBAR1 | Q8TDU6 | 7/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | SHBG | P04278 | 4/20 | 0.41 |
| ▸ | SERPINA6 | P08185 | 3/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.39 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.39 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.39 |
| ▸ | OSBP | P22059 | 1/20 | 0.39 |
| ▸ | OSBP2 | Q969R2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10402248 | 1.00 | SRD5A2 (0.42) | SRD5A2GPBAR1CYP3A4SHBGSERPINA6 | |
| SCHEMBL10404158 | 0.88 | SRD5A2 (0.41) | SRD5A2GPBAR1CYP3A4SHBGSERPINA6 | |
| SCHEMBL11043325 | 0.83 | GPBAR1 (0.59) | GPBAR1CYP3A4SHBGSERPINA6NR3C1 | |
| SCHEMBL11043329 | 0.83 | GPBAR1 (0.59) | GPBAR1CYP3A4SHBGSERPINA6NR3C1 | |
| SCHEMBL10404132 | 0.80 | SRD5A2 (0.42) | SRD5A2GPBAR1CYP3A4SHBGSERPINA6 | |
| SCHEMBL11042029 | 0.74 | CYP19A1 (0.66) | GPBAR1CYP3A4SHBGSERPINA6CYP19A1 | |
| SCHEMBL3988004 | 0.74 | CYP19A1 (0.66) | GPBAR1CYP3A4SHBGSERPINA6CYP19A1 | |
| SCHEMBL11126643 | 0.74 | CYP19A1 (0.50) | SRD5A2GPBAR1CYP3A4CYP19A1LMNA | |
| SCHEMBL11042638 | 0.74 | CYP19A1 (0.50) | SRD5A2GPBAR1CYP3A4CYP19A1LMNA | |
| SCHEMBL10402779 | 0.73 | CYP19A1 (0.51) | GPBAR1CYP3A4SHBGSERPINA6CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4898694-A | 17-Hydroxy-steroids | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 1990-02-06 | — | — | US | disclosed |