Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | TP53 | P04637 | 3/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | THRB | P10828 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11403626 | 0.79 | TSHR (0.55) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL17368676 | 0.78 | TSHR (0.53) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL10406673 | 0.78 | TSHR (0.53) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL10044296 | 0.78 | TSHR (0.53) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL10611047 | 0.78 | TSHR (0.53) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL93462 | 0.77 | TSHR (0.84) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL30604742 | 0.77 | TSHR (0.84) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL7783160 | 0.76 | F2 (0.34) | TSHRALDH1A1 | |
| SCHEMBL289840 | 0.76 | CYP3A4 (0.52) | TSHRALDH1A1TP53HSD17B10CYP3A4 | |
| SCHEMBL10508670 | 0.75 | TSHR (0.80) | TSHRALDH1A1TP53HIF1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-60166307-A | — | — | None | — | — | JP | disclosed |
| US-4921890-A | Process for improving polymer substrate properties, and flame retardancy modified polymers produced thereby | INTERA COMPANY, LTD. (US) | 1990-05-01 | — | — | US | disclosed |
| EP-0294531-A2 | Treatment of polymer substrates | Intera Company, Ltd (US) | 1988-12-14 | — | — | EP | disclosed |
| EP-0187958-A2 | Resin for information recording medium | TORAY INDUSTRIES, INC. (JP) | 1986-07-23 | — | — | EP | disclosed |
| JP-S60166307-A | PLASTIC MATERIAL FOR OPTICAL USE | AGENCY OF IND SCIENCE & TECHNOL | 1985-08-29 | — | — | JP | disclosed |