Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.41 |
| ▸ | MAPT | P10636 | 11/20 | 0.38 |
| ▸ | RAB9A | P51151 | 9/20 | 0.38 |
| ▸ | NPC1 | O15118 | 8/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.37 |
| ▸ | HPGD | P15428 | 6/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8288618 | 0.80 | KDM4E (0.61) | KDM4EMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL9822430 | 0.78 | PDE2A (0.42) | KDM4EMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL10407365 | 0.78 | KDM4E (0.71) | KDM4EMAPTSMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL10407273 | 0.77 | KDM4E (0.41) | KDM4EMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL19455177 | 0.77 | MAPT (0.59) | KDM4EMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL26253982 | 0.74 | TYK2 (0.45) | KDM4EMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL12697196 | 0.73 | HPGD (0.54) | KDM4EMAPTSMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL21200356 | 0.72 | KDM4E (0.55) | KDM4EMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL11962837 | 0.72 | HSD17B10 (0.64) | KDM4EMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL11962825 | 0.70 | KMT2A (0.48) | KDM4EMAPTRAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4966900-A | FOR MICROBISM THERAPY, BACTERIAL INFECTIONS | SANKEI PHARMACEUTICAL COMPANY LTD. (JP) | 1990-10-30 | — | — | US | disclosed |
| EP-0254495-A2 | Beta-Lactam compound, method for preparing the same, medicinal composition for bacterially infectious disease therapy containing the same and intermediates for synthesis of the same | SANKEI PHARMACEUTICAL COMPANY LIMITED (JP) | 1988-01-27 | — | — | EP | disclosed |