Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28223158 | 1.00 | HTT (0.67) | HTTMAPTP2RX7L3MBTL1GAA | |
| SCHEMBL30945806 | 1.00 | HTT (0.67) | HTTMAPTP2RX7L3MBTL1GAA | |
| SCHEMBL11508665 | 1.00 | HTT (0.67) | HTTMAPTP2RX7L3MBTL1GAA | |
| SCHEMBL25278390 | 1.00 | HTT (0.67) | HTTMAPTP2RX7L3MBTL1GAA | |
| SCHEMBL10407897 | 1.00 | HTT (0.67) | HTTMAPTP2RX7L3MBTL1GAA | |
| SCHEMBL25229719 | 1.00 | HTT (0.67) | HTTMAPTP2RX7L3MBTL1GAA | |
| SCHEMBL3689657 | 1.00 | HTT (0.67) | HTTMAPTP2RX7L3MBTL1GAA | |
| SCHEMBL3682496 | 1.00 | HTT (0.67) | HTTMAPTP2RX7L3MBTL1GAA | |
| SCHEMBL3631573 | 1.00 | HTT (0.67) | HTTMAPTP2RX7L3MBTL1GAA | |
| SCHEMBL3678590 | 1.00 | HTT (0.67) | HTTMAPTP2RX7L3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4925984-A | REACTION WITH BROMINE IN SOLUTION | ETHYL CORPORATION (US) | 1990-05-15 | — | — | US | disclosed |