SCHEMBL10410690

SCHEMBL10410690

CC1CCCC(O)C(O)C1

nearest known ligand 0.50

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.50
TRPM8 Q7Z2W7 2/20 0.50
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
CA4 P22748 2/20 0.50
MGLL Q99685 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17988180 0.82
SCHEMBL27353412 0.82
SCHEMBL20863050 0.82
SCHEMBL8367331 0.82
SCHEMBL6346650 0.82
SCHEMBL14724776 0.82
SCHEMBL10306743 0.82
SCHEMBL6349621 0.82
SCHEMBL13645852 0.82
SCHEMBL881181 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4939258-A Cycloalkanol esters of dihydrolysergic acid ELI LILLY AND COMPANY (US) 1990-07-03 US disclosed
US-4906639-A Cycloalkanol esters of dihydrolysergic acid ELI LILLY AND COMPANY (US) 1990-03-06 US disclosed
US-4845224-A Cycloalkanol esters of dihydrolysergic acid having peripheral serotonin antagonist properties ELI LILLY AND COMPANY (US) 1989-07-04 US disclosed
US-4810710-A SEROTONIN BLOCKERS ELI LILLY AND COMPANY (US) 1989-03-07 US disclosed
US-4762842-A SEROTONIN ANTAGONIST ELI LILLY AND COMPANY (US) 1988-08-09 US disclosed
US-4713384-A HYPOTENSIVE AND ANTIMIGRAINE AGENTS ELI LILLY AND COMPANY (US) 1987-12-15 US disclosed
US-4683236-A ANTISEROTONIN AGENTS ELI LILLY AND COMPANY (US) 1987-07-28 US disclosed