Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10411401 | 0.89 | GAA (0.44) | GAAPKMTSHR | |
| SCHEMBL10411392 | 0.82 | GAA (0.42) | GAAPKMTSHRRNASEH1 | |
| SCHEMBL10411634 | 0.77 | — | — | |
| SCHEMBL12020194 | 0.76 | PTGS1 (0.42) | — | |
| SCHEMBL10411636 | 0.74 | — | — | |
| SCHEMBL10411393 | 0.74 | GAA (0.42) | GAAPKMTSHR | |
| SCHEMBL6367925 | 0.72 | — | — | |
| SCHEMBL10868107 | 0.69 | — | — | |
| Bromide SCHEMBL10411927 | 0.69 | — | — | |
| SCHEMBL6345069 | 0.68 | HMGB1 (0.47) | GAAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0178413-A1 | Benzimidazoles | BEECHAM GROUP PLC (GB) | 1986-04-23 | — | — | EP | claimed |
| US-4925853-A | Antiinflammatory, antiallergens, antiulcer agents | BEECHAM GROUP PLC (GB) | 1990-05-15 | — | — | US | disclosed |
| EP-0178413-A1 | Benzimidazoles | BEECHAM GROUP PLC (GB) | 1986-04-23 | — | — | EP | disclosed |