Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.47 |
| ▸ | MGMT | P16455 | 1/20 | 0.47 |
| ▸ | HPD | P32754 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10730419 | 0.90 | MAPT (0.54) | MAPTMEN1KMT2ATDP1MAPK1 | |
| SCHEMBL647866 | 0.88 | TDP1 (0.56) | MAPTMEN1KMT2ATDP1MAPK1 | |
| SCHEMBL14228268 | 0.83 | MGMT (0.48) | MAPTMEN1KMT2ATDP1MAPK1 | |
| SCHEMBL15013285 | 0.82 | MAPT (0.55) | MAPTMEN1KMT2ATDP1MAPK1 | |
| SCHEMBL3614237 | 0.81 | MAPT (0.49) | MAPTMEN1KMT2ATDP1MAPK1 | |
| SCHEMBL7882348 | 0.81 | MAPT (0.49) | MAPTMEN1KMT2ATDP1MAPK1 | |
| SCHEMBL27896267 | 0.79 | MAPT (0.47) | MAPTMEN1KMT2AL3MBTL1CYP19A1 | |
| SCHEMBL1162221 | 0.79 | PTGER1 (0.54) | MAPTMEN1KMT2ATDP1MAPK1 | |
| SCHEMBL25726044 | 0.78 | MAPT (0.49) | MAPTMEN1KMT2ATDP1MAPK1 | |
| SCHEMBL7881426 | 0.78 | MAPT (0.46) | MAPTMEN1KMT2ATDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4925853-A | Antiinflammatory, antiallergens, antiulcer agents | BEECHAM GROUP PLC (GB) | 1990-05-15 | — | — | US | disclosed |
| EP-0284686-A1 | Condensed triazoles, their preparation and their use as medicines | BEECHAM GROUP PLC (GB) | 1988-10-05 | — | — | EP | disclosed |
| EP-0178413-A1 | Benzimidazoles | BEECHAM GROUP PLC (GB) | 1986-04-23 | — | — | EP | disclosed |